Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	90933
Country	Italy

Received	2023-12-18 07:57
Peer-Review Started	2023-12-18 07:57
To Make the First Decision
Return for Revision	2024-01-11 05:26
Revised	2024-01-20 19:59
Second Decision	2024-02-28 02:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-02-28 08:07
Articles in Press	2024-02-28 08:07
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-02-25 09:48
Typeset the Manuscript	2024-03-18 01:43
Publish the Manuscript Online	2024-03-18 06:45

ISSN	2150-5349 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	New paradigm of oral rehydration in patients affected by irritable bowel syndrome with chronic diarrhea
Manuscript Source	Invited Manuscript
All Author List	Marco Chiarelli, Matilde De Simone, Gerardo Cioffi and Ugo Cioffi
ORCID	Author(s) ORCID Number Marco Chiarelli http://orcid.org/0000-0003-1729-4925 Matilde De Simone http://orcid.org/0000-0002-3763-4416 Gerardo Cioffi http://orcid.org/0000-0001-6751-3335 Ugo Cioffi http://orcid.org/0000-0002-5321-5828
Funding Agency and Grant Number
Corresponding Author	Marco Chiarelli, MD, Researcher, Department of Emergency and Robotic Surgery, A. Manzoni Hospital–ASST Lecco, Lecco via Dell’Eremo 9/11, Lecco 23900, Italy. m.chiarelli@asst-lecco.it
Key Words	Diarrhea; Irritable bowel syndrome; Diarrhea-predominant irritable bowel syndrome; Medical food; Amino acid beverage formulation
Core Tip	Amino acid based solution has shown promising results in improving symptoms of chemotherapy related diarrhea. Irritable bowel syndrome with diarrhea is a very frequent gastrointestinal disorder. A recent study has been conducted to evaluate the clinical impact of the amino acid based medical beverage on the symptoms of diarrhea predominant irritable bowel syndrome with a real-life methodology. The amino acid based medical beverage seems to be well tolerated and improve gastrointestinal symptoms. The results of this study are very promising and the amino acid based solution will likely become part of the standard treatment for chronic recurrent diarrhea in the near future.
Publish Date	2024-03-18 06:45
Citation	Chiarelli M, De Simone M, Cioffi G, Cioffi U. New paradigm of oral rehydration in patients affected by irritable bowel syndrome with chronic diarrhea. World J Gastrointest Pharmacol Ther 2024; 15(1): 90933
URL	https://www.wjgnet.com/2150-5349/full/v15/i1/90933.htm
DOI	https://dx.doi.org/10.4292/wjgpt.v15.i1.90933

Full Article (PDF)	WJGPT-15-90933-with-cover.pdf
Manuscript File	90933_Auto_Edited-LJH_WangTQ-YJP.docx
Answering Reviewers	90933-Answering reviewers.pdf
Audio Core Tip	90933-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	90933-Conflict-of-interest statement.pdf
Copyright License Agreement	90933-Copyright license agreement.pdf
Peer-review Report	90933-Peer-review(s).pdf
Scientific Misconduct Check	90933-Bing-Liu JH-2.png
Scientific Misconduct Check	90933-CrossCheck.png
Scientific Editor Work List	90933-Scientific editor work list.pdf