BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
4/3/2024 7:21:13 AM | Browse: 91 | Download: 393
 |
Received |
|
2023-12-30 13:56 |
 |
Peer-Review Started |
|
2023-12-30 13:56 |
 |
To Make the First Decision |
|
|
 |
Return for Revision |
|
2024-01-16 08:09 |
 |
Revised |
|
2024-02-03 09:55 |
 |
Second Decision |
|
2024-03-14 02:43 |
 |
Accepted by Journal Editor-in-Chief |
|
|
 |
Accepted by Executive Editor-in-Chief |
|
2024-03-14 04:11 |
 |
Articles in Press |
|
2024-03-14 04:11 |
 |
Publication Fee Transferred |
|
|
 |
Edit the Manuscript by Language Editor |
|
|
 |
Typeset the Manuscript |
|
2024-03-28 01:50 |
 |
Publish the Manuscript Online |
|
2024-04-03 07:21 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Editorial |
Article Title |
Cellular strategies to induce immune tolerance after liver transplantation: Clinical perspectives
|
Manuscript Source |
Invited Manuscript |
All Author List |
Ai-Wei Zhou, Jing Jin and Yuan Liu |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
the National Natural Science Foundation of China |
82000586 and 82241221 |
Shanghai Immune Therapy Institute |
|
|
Corresponding Author |
Yuan Liu, MD, Assistant Professor, Department of Liver Surgery, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 160 Pujian Road, Shanghai 200127, China. liuyuanbird@163.com |
Key Words |
Cellular therapy; Induced tolerance; Liver transplantation; Regulatory T cells; Regulatory dendritic cells |
Core Tip |
Immune tolerance after liver transplantation could significantly reduce the long-term side-effects of immunosuppressants. Compared with operational and spontaneous tolerance, induced tolerance by cellular therapy could reduce immunosuppressant dosage at early stage after transplantation. Regulatory immune cells could suppress the inflammatory response, which are widely explored in preclinical and clinical trials. So far, regulatory CD4+ T cells, mesenchymal stromal cells and regulatory dendritic cells are mostly studied. However, even the safety and tolerability of cellular therapy in transplantation recipients have been validated, the overall efficacy of tolerance induction is unsatisfactory. Detailed exploration is required in the future. |
Publish Date |
2024-04-03 07:21 |
Citation |
Zhou AW, Jin J, Liu Y. Cellular strategies to induce immune tolerance after liver transplantation: Clinical perspectives. World J Gastroenterol 2024; 30(13): 1791-1800 |
URL |
https://www.wjgnet.com/1007-9327/full/v30/i13/1791.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v30.i13.1791 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345