Publication Name	World Journal of Hepatology
Manuscript ID	9511
Country	Italy

Received	2014-02-15 21:34
Peer-Review Started	2014-02-15 23:32
To Make the First Decision	2014-03-26 15:26
Return for Revision	2014-04-02 20:45
Revised	2014-05-07 22:03
Second Decision	2014-06-11 14:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-11 14:27
Articles in Press	2014-06-11 15:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-28 14:01
Publish the Manuscript Online	2014-08-29 07:54

ISSN	1948-5182 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Review
Article Title	Vertical hepatitis C virus transmission: Main questions and answers
Manuscript Source	Unsolicited Manuscript
All Author List	Grazia Tosone, Alberto Enrico Maraolo, Silvia Mascolo, Giulia Palmiero, Orsola Tambaro and Raffaele Orlando
Funding Agency and Grant Number
Corresponding Author	Grazia Tosone, MD, Department of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Via Sergio Pansini 5, 80131 Napoli, Italy. grazia.tosone@unina.it
Key Words	Hepatitis C infection; Pregnancy; Vertical transmission; Antiviral therapy; Prevention
Core Tip	Hepatitis C virus (HCV) infection during pregnancy is an emerging problem. While not negatively affecting acute hepatitis, it may exacerbate chronic hepatitis and worsen liver function in woman with liver cirrhosis. HCV does not affect delivery outcome apart from an increased risk of premature membrane rupture and cesarean delivery. The mother-to-child HCV transmission rate is low (3%-5%) and is related to high maternal viremia, human immunodeficiency virus (HIV) coinfection, prolonged rupture of membranes, vaginal lacerations and invasive fetal monitoring. Cesarean delivery and no breastfeeding are indicated for HIV/HCV coinfected women. Antiviral therapy is not routinely offered to pregnant women and infants because of its side effects.
Publish Date	2014-08-29 07:54
Citation	Tosone G, Maraolo AE, Mascolo S, Palmiero G, Tambaro O, Orlando R. Vertical hepatitis C virus transmission: Main questions and answers. World J Hepatol 2014; 6(8): 538-548
URL	http://www.wjgnet.com/1948-5182/full/v6/i8/538.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i8.538

Full Article (PDF)	WJH-6-538.pdf
Full Article (Word)	WJH-6-538.doc
Manuscript File	9511-Review.docx
Answering Reviewers	9511-Answering reviewers.pdf
Copyright License Agreement	9511-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9511-Language certificate.pdf
Peer-review Report	9511-Peer review(s).pdf
Scientific Misconduct Check	9511-CrossCheck.jpg
Scientific Editor Work List	9511-Scientific editor work list.pdf