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Publication Name World Journal of Hepatology
Manuscript ID 9511
Country/Territory Italy
Received
2014-02-15 21:34
Peer-Review Started
2014-02-15 23:32
To Make the First Decision
2014-03-26 15:26
Return for Revision
2014-04-02 20:45
Revised
2014-05-07 22:03
Second Decision
2014-06-11 14:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-06-11 14:27
Articles in Press
2014-06-11 15:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-08-28 14:01
Publish the Manuscript Online
2014-08-29 07:54
ISSN 1948-5182 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Review
Article Title Vertical hepatitis C virus transmission: Main questions and answers
Manuscript Source Unsolicited Manuscript
All Author List Grazia Tosone, Alberto Enrico Maraolo, Silvia Mascolo, Giulia Palmiero, Orsola Tambaro and Raffaele Orlando
Funding Agency and Grant Number
Corresponding Author Grazia Tosone, MD, Department of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Via Sergio Pansini 5, 80131 Napoli, Italy. grazia.tosone@unina.it
Key Words Hepatitis C infection; Pregnancy; Vertical transmission; Antiviral therapy; Prevention
Core Tip Hepatitis C virus (HCV) infection during pregnancy is an emerging problem. While not negatively affecting acute hepatitis, it may exacerbate chronic hepatitis and worsen liver function in woman with liver cirrhosis. HCV does not affect delivery outcome apart from an increased risk of premature membrane rupture and cesarean delivery. The mother-to-child HCV transmission rate is low (3%-5%) and is related to high maternal viremia, human immunodeficiency virus (HIV) coinfection, prolonged rupture of membranes, vaginal lacerations and invasive fetal monitoring. Cesarean delivery and no breastfeeding are indicated for HIV/HCV coinfected women. Antiviral therapy is not routinely offered to pregnant women and infants because of its side effects.
Publish Date 2014-08-29 07:54
Citation Tosone G, Maraolo AE, Mascolo S, Palmiero G, Tambaro O, Orlando R. Vertical hepatitis C virus transmission: Main questions and answers. World J Hepatol 2014; 6(8): 538-548
URL http://www.wjgnet.com/1948-5182/full/v6/i8/538.htm
DOI http://dx.doi.org/10.4254/wjh.v6.i8.538
Full Article (PDF) WJH-6-538.pdf
Full Article (Word) WJH-6-538.doc
Manuscript File 9511-Review.docx
Answering Reviewers 9511-Answering reviewers.pdf
Copyright License Agreement 9511-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 9511-Language certificate.pdf
Peer-review Report 9511-Peer review(s).pdf
Scientific Misconduct Check 9511-CrossCheck.jpg
Scientific Editor Work List 9511-Scientific editor work list.pdf