Publication Name	World Journal of Gastroenterology
Manuscript ID	9861
Country	Canada

Received	2014-03-02 17:03
Peer-Review Started	2014-03-02 19:05
To Make the First Decision	2014-03-27 21:01
Return for Revision	2014-03-31 10:10
Revised	2014-04-29 00:00
Second Decision	2014-05-26 21:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-26 21:57
Articles in Press	2014-05-26 22:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-28 09:53
Publish the Manuscript Online	2014-11-17 15:12

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Interplay between intestinal alkaline phosphatase, diet, gut microbes and immunity
Manuscript Source	Invited Manuscript
All Author List	Mehrbod Estaki, Daniella DeCoffe and Deanna L Gibson
Funding Agency and Grant Number	Funding Agency Grant Number Crohn’s and Colitis Foundation of Canada 11883 1486 RR 0001 Natural Science and Engineering Research Council and the Intestinal Diseases Education Awareness Society 86435 5557 RR0001
Corresponding Author	Deanna L Gibson, PhD, Assistant Professor, Department of Biology, University of British Columbia Okanagan, Kelowna V1V 1V7, British Columbia, Canada. deanna.gibson@ubc.ca
Key Words	Intestinal alkaline phosphatase; Inflammation; Infection; Lipopolysaccharides; Inflammatory disease; Intestinal microbiota; Diet
Core Tip	Intestinal alkaline phosphatase (IAP) is important for intestinal health. IAP’s role in the intestine encompasses both protection from systemic infections and chronic inflammatory diseases such as inflammatory bowel disease. There is a complex interplay occurring between IAP, diet, microbiota and the intestinal epithelium which has accelerated research on IAP as a potential therapeutic against these inflictions. The purpose of this review is to highlight the essential characteristics of IAP in maintaining homeostasis in the intestines while addressing the complex interplay between IAP, diet, microbiota and the intestinal epithelium.
Publish Date	2014-11-17 15:12
Citation	Estaki M, DeCoffe D, Gibson DL. Interplay between intestinal alkaline phosphatase, diet, gut microbes and immunity. World J Gastroenterol 2014; 20(42): 15650-15656
URL	http://www.wjgnet.com/1007-9327/full/v20/i42/15650.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i42.15650

Full Article (PDF)	WJG-20-15650.pdf
Full Article (Word)	WJG-20-15650.doc
Manuscript File	9861-Review.docx
Answering Reviewers	9861-Answering reviewers.pdf
Copyright License Agreement	9861-Copyright assignment.pdf
Peer-review Report	9861-Peer review.pdf
Scientific Misconduct Check	9861-CrossCheck.jpg
Scientific Editor Work List	9861-Scientific editor work list.pdf