| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Upper-gastrointestinal bleeding secondary to peptic ulcer disease: Incidence and outcomes
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Samuel Quan, Alexandra Frolkis, Kaylee Milne, Natalie Molodecky, Hong Yang, Elijah Dixon, Chad G Ball, Robert P Myers, Subrata Ghosh, Robert Hilsden, Sander Veldhuyzen van Zanten and Gilaad G Kaplan |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Summer studentships (2010, 2011, and 2012) by Alberta Innovates - Health Solutions |
|
|
| Corresponding Author |
Gilaad G Kaplan, MD, MPH, FRCPC, Associate Professor, Departments of Medicine, University of Calgary, 3280 Hospital Drive NW, Room 6D56, Calgary, AB T2N-4N1, Canada. ggkaplan@ucalgary.ca |
| Key Words |
Epidemiology; Peptic ulcer hemorrhage; Digestive system surgical procedures; Mortality; Endoscopy; Validation studies; Incidence |
| Core Tip |
In our population-based study the overall risk of surgery, in-hospital mortality, and 30-d readmission for hospitalized upper gastrointestinal bleeding (UGIB) secondary to peptic ulcer disease (PUD) was 4.3%, 8.5%, and 4.7%, respectively. Duodenal ulcers had a worse prognosis than gastric ulcers. Readmission was more common among rural residents, which might be due to decreased access to resources or practice differences between urban and rural centers. Interventional radiology was uncommonly utilized (0.6%) and limited to urban centers, but prevented surgery in 3/4 of patients. These findings suggest that greater access to medical services may improve outcomes for UGIB secondary to PUD. |
| Publish Date |
2014-12-18 17:08 |
| Citation |
Quan S, Frolkis A, Milne K, Molodecky N, Yang H, Dixon E, Ball CG, Myers RP, Ghosh S, Hilsden R, van Zanten SV, Kaplan GG. Upper-gastrointestinal bleeding secondary to peptic ulcer disease: Incidence and outcomes. World J Gastroenterol 2014; 20(46): 17568-17577 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i46/17568.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i46.17568 |
