Publication Name	World Journal of Gastroenterology
Manuscript ID	9900
Country	United States

Received	2014-03-03 16:02
Peer-Review Started	2014-03-03 18:21
To Make the First Decision	2014-03-27 20:58
Return for Revision	2014-03-31 10:22
Revised	2014-04-14 00:00
Second Decision	2014-05-26 21:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-26 21:41
Articles in Press	2014-05-26 22:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-14 12:11
Publish the Manuscript Online	2014-10-01 20:25

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Topic Highlights
Article Title	Anal squamous cell carcinoma: An evolution in disease and management
Manuscript Source	Invited Manuscript
All Author List	Marc C Osborne, Justin Maykel, Eric K Johnson and Scott R Steele
Funding Agency and Grant Number
Corresponding Author	Scott R Steele, MD, FACS, FASCRS, Chief, 9040a Fitzsimmons Dr Department of Surgery, Madigan Army Medical Center, Tacoma, WA 98431, United States. harkersteele@mac.com
Key Words	Anal cancer; Squamous cell cancer; Nigro protocol; Anal intraepithelial neoplasia; Chemoradiation therapy; Anal neoplasm; Radiotherapy; Cancer screening; Drug therapy
Core Tip	Despite advances in the diagnosis and management, we continue to see a steady rise in the incidence of anal squamous cell cancer. The management of anal cancer has evolved from mandatory surgery to sphincter preserving therapy and is now entering an era of screening and prevention. Chemoradiotherapy remains the primary therapy for anal cancer. Anal Pap smear and high-resolution anoscopy are emerging technologies for identification of precancerous lesions. A high index of suspicion and knowledge of the relevant anatomy and pathophysiology are essential to identify at risk group, avoid missed diagnosis, and provide proper counseling.
Publish Date	2014-10-01 20:25
Citation	Osborne MC, Maykel J, Johnson EK, Steele SR. Anal squamous cell carcinoma: An evolution in disease and management. World J Gastroenterol 2014; 20(36): 13052-13059
URL	http://www.wjgnet.com/1007-9327/full/v20/i36/13052.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i36.13052

Full Article (PDF)	WJG-20-13052.pdf
Full Article (Word)	WJG-20-13052.doc
Manuscript File	9900-Review.docx
Answering Reviewers	9900-Answering reviewers.pdf
Copyright License Agreement	9900-Copyright assignment.pdf
Peer-review Report	9900-Peer review.pdf
Scientific Misconduct Check	9900-CrossCheck.jpg
Scientific Editor Work List	9900-Scientific editor work list.pdf