Publication Name	World Journal of Gastroenterology
Manuscript ID	9991
Country	Netherlands

Received	2014-03-08 19:29
Peer-Review Started	2014-03-10 09:26
To Make the First Decision	2014-04-15 19:36
Return for Revision	2014-04-21 19:57
Revised	2014-04-30 01:38
Second Decision	2014-09-30 10:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-30 10:22
Articles in Press	2014-09-30 10:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-27 20:10
Publish the Manuscript Online	2014-12-18 17:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Hematopoietic stem cell transplantation for non-malignant gastrointestinal diseases
Manuscript Source	Invited Manuscript
All Author List	Abdulbaqi Al-toma, Petula Nijeboer, Gerd Bouma, Otto Visser and Chris JJ Mulder
Funding Agency and Grant Number
Corresponding Author	Abdulbaqi Al-toma, MD, PhD, Gastroenterologist, Department of internal medicine and gastroenterology, St. Antonius hospital, Koekoeslaan 1, 3430 EM Nieuwegein, The Netherlands. a.altoma@antoniusziekenhuis.nl
Key Words	Hematopoietic stem cell transplantation; Mesenchymal stem cells; Non-malignant gastrointestinal diseases; Celiac disease; Refractory celiac disease; Lymphoma; Crohn’s; Ulcerative colitis; Cirrhosis
Core Tip	Hematopoietic stem cell transplantation (HSCT) can be used to treat malignant and non-malignant diseases. This therapeutic modality is based on using immunoablation followed by reinfusion of hematopoietic progenitor cells to regenerate naive T-lymphocytes. HSCT and mesenchymal SCT have been proved successful in treating refractory inflammatory conditions such as Crohn’s disease and refractory celiac disease type Ⅱ. The ultimate target of aggressively treating this type of celiac disease is to prevent development of lymphoma. Data in end-stage liver diseases are also encouraging.
Publish Date	2014-12-18 17:08
Citation	Al-toma A, Nijeboer P, Bouma G, Visser O, Mulder CJJ. Hematopoietic stem cell transplantation for non-malignant gastrointestinal diseases. World J Gastroenterol 2014; 20(46): 17368-17375
URL	http://www.wjgnet.com/1007-9327/full/v20/i46/17368.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i46.17368

Full Article (PDF)	WJG-20-17368.pdf
Full Article (Word)	WJG-20-17368.doc
Manuscript File	9991-Review.docx
Answering Reviewers	9991-Answering reviewers.pdf
Copyright License Agreement	9991-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9991-Language certificate.pdf
Peer-review Report	9991-Peer review.pdf
Scientific Misconduct Check	9991-CorssCheck.jpg
Scientific Editor Work List	9991-Scientific editor work list.pdf