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12/10/2015 10:35:00 AM | Browse: 504 | Download: 481
Publication Name World Journal of Gastroenterology
Manuscript ID 13349
Country of Manuscript Source United States
Received
2014-08-19 08:28
Peer-Review Started
2014-08-20 14:24
To Make the First Decision
2014-09-27 15:11
Return for Revision
2014-10-11 16:47
Revised
2014-10-17 04:54
Second Decision
2014-12-02 07:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-12-16 10:11
Articles in Press
2014-12-16 10:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-03-09 20:01
Publish the Manuscript Online
2015-03-19 16:57
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Case Report
Article Title New therapeutic option for irritable bowel syndrome: Serum derived bovine immunoglobulin
Manuscript Source Unsolicited Manuscript
All Author List Larry Good, Roxanne Rosario and Raymond Panas
Funding Agency and Grant Number
Correspondence To Larry Good, MD, Department of Gastroenterology, No. 444 Merrick Road, Lynbrook, NY 11563, United States. good1b@optonline.com
Keywords Irritable bowel syndrome; Diarrhea; Immunoglobulin; Bovine; Serum derived; Gastrointestinal disease; Medical food
Core Tip Oral prescription medical foods are becoming part of the outpatient medical practice and are finding new uses as a therapeutic option for gastrointestinal disorders. This case series investigates the use of oral serum-derived bovine immunoglobulin/protein isolate (SBI) in the management of differing forms of irritable bowel syndrome (IBS). Because of the multifaceted mechanism of action, SBI provides a distinct protein source to normalize bowel function, gastrointestinal microbiota, and nutritionally enhance tight junction protein expression. As such, there may be potential use for patients with other forms of IBS besides IBS-D. Additional research is needed to explore this use.
Publish Date 2015-03-19 16:57
Citation Good L, Rosario R, Panas R. New therapeutic option for irritable bowel syndrome: Serum-derived bovine immu­noglobulin. World J Gastroenterol 2015; 21(11): 3361-3366
Url http://www.wjgnet.com/1007-9327/full/v21/i11/3361.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i11.3361
Full Article (PDF) WJG-21-3361.pdf
Full Article (Word) WJG-21-3361.doc
Manuscript File 13349-Review.docx
Answering Reviewers 13349-Answering reviewers.pdf
Copyright License Agreement 13349-Copyright assignment.pdf
Peer-review Report 13349-Peer review(s).pdf
Scientific Misconduct Check 13349-CrossCheck.jpg
Scientific Editor Work List 13349-Scientific editor work list.pdf