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Publication Name World Journal of Hepatology
Manuscript ID 13641
Country of Manuscript Source Taiwan
Received
2014-08-28 17:54
Peer-Review Started
2014-08-28 19:00
To Make the First Decision
2014-12-17 11:38
Return for Revision
2014-12-19 10:49
Revised
2014-12-22 12:31
Second Decision
2015-03-16 17:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-04-02 16:06
Articles in Press
2015-04-02 16:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-05-15 10:02
Publish the Manuscript Online
2015-06-03 12:00
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Virology
Manuscript Type Review
Article Title Hepatitis C virus: Virology, diagnosis and treatment
Manuscript Source Invited Manuscript
All Author List Hui-Chun Li and Shih-Yen Lo
Funding Agency and Grant Number
Funding Agency Grant Number
National Science Council of Taiwan NSC 101-2320-B-320-011-MY3 (Dr. Shih-Yen Lo)
Tzu Chi University TCIRP 103002-03 (to Dr. Shih-Yen Lo)
Tzu Chi University TCIRP 103002-02 (to Dr. Hui-Chun Li)
Corresponding author Dr. Shih-Yen Lo, Department of Laboratory Medicine and Biotechnology, Tzu Chi University, 701, Section 3, Chung Yang Road, Hualien 97004, Taiwan. losylo@mail.tcu.edu.tw
Keywords Hepatitis C virus; Diagnosis; Treatment; Hepatocellular carcinoma; Nucleic acid test; Enzyme immunoassay; Interferon; Direct acting antivirals; Host-targeted agents; Sofosbuvir
Core Tip Understanding the general properties of hepatitis C virus (HCV) viral RNA and proteins facilitates the development of sensitive diagnostic tools and effective antiviral treatments. At present, serologic screening test is recommended to perform on individuals in the high risk groups and nucleic acid tests are re-commended to confirm the active HCV infections. To 2014, in addition to pegylated interferon and ribavirin, boceprevir, telaprevir, simeprevir, sofosbuvir and Harvoni are approved by Food and Drug Administration to treat HCV infections. The majority of HCV infections can be cured by these anti-viral treatments. An efficient prophylactic vaccine will be the next challenge in the fight against HCV infection.
Publish Date 2015-06-03 12:00
Citation Li HC, Lo SY. Hepatitis C virus: Virology, diagnosis and treatment. World J Hepatol 2015; 7(10): 1377-1389
Url http://www.wjgnet.com/1948-5182/full/v7/i10/1377.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i10.1377
Full Article (PDF) WJH-7-1377.pdf
Full Article (Word) WJH-7-1377.doc
Manuscript File 13641-Review.docx
Answering Reviewers 13641-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 13641-Conflict-of-interest statement.pdf
Copyright License Agreement 13641-Copyright assignment.pdf
Peer-review Report 13641-Peer-review(s).pdf
Scientific Misconduct Check 13641-Scientific misconduct check.pdf
Scientific Editor Work List 13641-Scientific editor work list.pdf