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5/21/2015 2:15:00 PM | Browse: 631 | Download: 629
Publication Name World Journal of Experimental Medicine
Manuscript ID 14451
Country/Territory Japan
Received
2014-10-04 16:50
Peer-Review Started
2014-10-05 09:13
To Make the First Decision
2014-12-12 17:29
Return for Revision
2014-12-16 11:50
Revised
2014-12-23 10:41
Second Decision
2015-01-04 16:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-02-09 09:59
Articles in Press
2015-02-09 09:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-02-27 20:30
Typeset the Manuscript
2015-04-22 16:05
Publish the Manuscript Online
2015-05-21 14:15
ISSN 2220-315x (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Asymmetric dimethylarginine, a biomarker of cardiovascular complications in diabetes mellitus
Manuscript Source Invited Manuscript
All Author List Hiroyuki Konya, Masayuki Miuchi, Kahori Satani, Satoshi Matsutani, Yuzo Yano, Taku Tsunoda, Takashi Ikawa, Toshihiro Matsuo, Fumihiro Ochi, Yoshiki Kusunoki, Masaru Tokuda, Tomoyuki Katsuno, Tomoya Hamaguchi, Jun-ichiro Miyagawa and Mitsuyoshi Namba
Funding Agency and Grant Number
Corresponding author Hiroyuki Konya, MD, PhD, Department of Internal Medicine, Ashiya Municipal Hospital, 39-1, Asahigaoka-cho, Ashiya, Hyogo 659-8502, Japan. h-dyer@mvi.biglobe.ne.jp
Keywords Asymmetric dimethylarginine; Biomarker; Diabetes mellitus; Cardiovascular complications; Incretin
Core Tip Asymmetric dimethylarginine (ADMA) is an emerging independent biomarker for prospective cardiovascular (CV) complications. In our study, the results show that the cases with a high level of ADMA could have diabetes mellitus CV (DMCV) complications in the future within five years. Furthermore, not only ADMA but also urinary albumin was associated with DMCV complications in the multiple regression analyses. The clinical acceptation of this parameter will rely on the availability of therapies to immediately reduce ADMA such as incretin-based drugs, which could support the part of ADMA as an etiologic risk factor.
Publish Date 2015-05-21 14:15
Citation Konya H, Miuchi M, Satani K, Matsutani S, Yano Y, Tsunoda T, Ikawa T, Matsuo T, Ochi F, Kusunoki Y, Tokuda M, Katsuno T, Hamaguchi T, Miyagawa J, Namba M. Asymmetric dimethylarginine, a biomarker of cardiovascular complications in diabetes mellitus. World J Exp Med 2015; 5(2): 110-119
Url http://www.wjgnet.com/2220-315X/full/v5/i2/110.htm
DOI http://dx.doi.org/10.5493/wjem.v5.i2.110
Full Article (PDF) WJEM-5-110.pdf
Full Article (Word) WJEM-5-110.doc
Manuscript File 14451-Review.docx
Answering Reviewers 14451-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 14451-Conflict-of-interest statement.pdf
Copyright License Agreement 14451-Copyright assignment.pdf
Peer-review Report 14451-Peer-review(s).pdf
Scientific Misconduct Check 14451-Scientific misconduct check.pdf
Scientific Editor Work List 14451-Scientific editor work list.pdf