| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Estimating steatosis and fibrosis: Comparison of acoustic structure quantification with established techniques
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Thomas Karlas, Joachim Berger, Nikita Garnov, Franziska Lindner, Harald Busse, Nicolas Linder, Alexander Schaudinn, Bettina Relke, Rima Chakaroun, Michael Tröltzsch, Johannes Wiegand and Volker Keim |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Federal Ministry of Education and Research (BMBF), Germany, FKZ: 01EO1001 |
K7-40 |
| German Research Foundation (DFG) |
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| University of Leipzig within the program of Open Access Publishing |
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| Corresponding Author |
Thomas Karlas, MD, Department of Medicine, Neurology and Dermatology, Division of Gastro enterology and Rheumatology, University Hospital Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany. thomas.karlas@medizin.uni-leipzig.de |
| Key Words |
Non-invasive characterization of hepatic steatosis and fibrosis is becoming important for the screening; diagnosis; ASQ could be used to evaluate steatosis and merits further investigation; however; ASQ seems to be impractical to characterize fibrosis in patients with fatty liver disease. |
| Core Tip |
Non-invasive characterization of hepatic steatosis and fibrosis is becoming important for the screening, diagnosis, and monitoring of patients with chronic liver diseases. This work compared acoustic structure quantification (ASQ) and established non-invasive methods to characterize fatty liver disease. ASQ parameters differed between healthy controls and diabetic patients with fatty liver disease independent of the extent of fibrosis. The focal disturbance ratio and further ASQ parameters correlated with the severity of steatosis. Therefore, ASQ could be used to evaluate steatosis and merits further investigation; however, ASQ seems to be impractical to characterize fibrosis in patients with fatty liver disease. |
| Publish Date |
2015-04-27 16:22 |
| Citation |
Karlas T, Berger J, Garnov N, Lindner F, Busse H, Linder N, Schaudinn A, Relke B, Chakaroun R, Tröltzsch M, Wiegand J, Keim V. Estimating steatosis and fibrosis: Comparison of acoustic structure quantification with established techniques. World J Gastroenterol 2015; 21(16): 4894-4902 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i16/4894.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i16.4894 |
