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4/7/2015 6:08:00 PM | Browse: 495 | Download: 901
Publication Name World Journal of Gastroenterology
Manuscript ID 15407
Country/Territory Japan
Received
2014-11-25 20:19
Peer-Review Started
2014-11-26 10:08
To Make the First Decision
2014-12-26 13:24
Return for Revision
2014-12-31 09:08
Revised
2015-01-08 11:15
Second Decision
2015-01-31 09:28
Accepted by Journal Editor-in-Chief
2015-02-02 10:43
Accepted by Company Editor-in-Chief
2015-02-05 17:10
Articles in Press
2015-02-05 17:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-02-27 21:35
Typeset the Manuscript
2015-03-23 16:03
Publish the Manuscript Online
2015-04-07 17:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Editorial
Article Title Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
Manuscript Source Invited Manuscript
All Author List Yoshihisa Takahashi, Keiichiro Sugimoto, Hiroshi Inui and Toshio Fukusato
Funding Agency and Grant Number
Corresponding author Yoshihisa Takahashi, Associate Professor, MD, Department of Pathology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan. ytakaha-tky@umin.ac.jp
Keywords Pharmacological therapy; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Vitamin E; Thiazolidinedione
Core Tip Nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) is considered to be a hepatic manifestation of metabolic syndrome. Currently, the principal treatment for NAFLD/NASH is lifestyle modification by diet and exercise. However, establishment of pharmacological therapy is indispensable. Currently, insulin sensitizers (thiazolidinediones) and antioxidants (vitamin E) seem to be the most promising agents for treating NAFLD/NASH, and lipid-lowering drugs, pentoxifylline, angiotensin receptor blockers, and n-3 polyunsaturated fatty acids also have promise. However, there is a lack of consensus regarding the most effective and appropriate pharmacotherapy for NAFLD/NASH. Here, we review the existing and potential pharmacological therapies for NAFLD/NASH.
Publish Date 2015-04-07 17:13
Citation Takahashi Y, Sugimoto K, Inui H, Fukusato T. Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Gastroenterol 2015; 21(13): 3777-3785
Url http://www.wjgnet.com/1007-9327/full/v21/i13/3777.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i13.3777
Full Article (PDF) WJG-21-3777.pdf
Full Article (Word) WJG-21-3777.doc
Manuscript File 15407-Review.docx
Answering Reviewers 15407-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 15407-Conflict-of-interest statement.pdf
Copyright License Agreement 15407-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 15407-Language certificate.pdf
Peer-review Report 15407-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 15407-Journal Editor-in-Chief's Review Report.pdf
Scientific Misconduct Check 15407-Scientific misconduct check.pdf
Scientific Editor Work List 15407-Scientific editor work list.pdf