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5/21/2015 2:15:00 PM | Browse: 420 | Download: 499
Publication Name World Journal of Experimental Medicine
Manuscript ID 15457
Country of Manuscript Source Germany
Received
2014-11-27 11:00
Peer-Review Started
2014-11-27 19:50
To Make the First Decision
2014-12-26 13:17
Return for Revision
2015-01-01 16:53
Revised
2015-01-09 01:49
Second Decision
2015-03-16 17:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-04-02 16:21
Articles in Press
2015-04-02 16:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-04-22 16:08
Publish the Manuscript Online
2015-05-21 14:15
ISSN 2220-315x (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Anesthesiology
Manuscript Type Review
Article Title Are there new approaches for diagnosis, therapy guidance and outcome prediction of sepsis?
Manuscript Source Invited Manuscript
All Author List Dubravka Kojic, Benedikt H Siegler, Florian Uhle, Christoph Lichtenstern, Peter P Nawroth, Markus A Weigand, Stefan Hofer and Thorsten Brenner
Funding Agency and Grant Number
Corresponding author Dr. Dubravka Kojic, Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany. dubravka.kojic@med.uni-heidelberg.de
Keywords Clinical decision-making; Biomarkers; Early prediction; Sepsis and mortality
Core Tip Sepsis is a complex continuum of disturbed systems. Despite the presence of clinical consensus criteria, the early diagnosis especially in the perioperative setting is challenging. A magnitude of potential new biomarkers is tested for this purpose, but evidence is mounting that due to the complex nature of the syndrome, biomarkers are rather complementary tools for clinical decision making than “magic bullets”. Moreover, biomarkers are also evaluated for therapy guidance, linking diagnostic results to an individual therapeutic regime. This review summarizes the developments in the biomarker field, aiming to provide an overview about current targets and their limitations.
Publish Date 2015-05-21 14:15
Citation Kojic D, Siegler BH, Uhle F, Lichtenstern C, Nawroth PP, Weigand MA, Hofer S, Brenner T. Are there new approaches for diagnosis, therapy guidance and outcome prediction of sepsis? World J Exp Med 2015; 5(2): 50-63
Url http://www.wjgnet.com/2220-315X/full/v5/i2/50.htm
DOI http://dx.doi.org/10.5493/wjem.v5.i2.50
Full Article (PDF) WJEM-5-50.pdf
Full Article (Word) WJEM-5-50.doc
Manuscript File 15457-Review.docx
Answering Reviewers 15457-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 15457-Conflict-of-interest statement.pdf
Copyright License Agreement 15457-Copyright assignment.pdf
Peer-review Report 15457-Peer-review(s).pdf
Scientific Misconduct Check 15457-Scientific misconduct check.pdf
Scientific Editor Work List 15457-Scientific editor work list.pdf