Publication Name	World Journal of Clinical Cases
Manuscript ID	16226
Country

Received	2015-01-05 08:56
Peer-Review Started	2015-01-07 19:23
To Make the First Decision	2015-01-20 13:32
Return for Revision	2015-01-30 17:09
Revised	2015-02-27 14:35
Second Decision	2015-03-16 17:40
Accepted by Journal Editor-in-Chief	2015-03-18 16:18
Accepted by Company Editor-in-Chief	2015-04-02 16:00
Articles in Press	2015-04-02 16:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-01 15:56
Publish the Manuscript Online	2015-06-19 16:35

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Rheumatology
Manuscript Type	Review
Article Title	Giant cell arteritis: Current treatment and management
Manuscript Source	Invited Manuscript
All Author List	Cristina Ponte, Ana Filipa Rodrigues, Lorraine O’Neill and Raashid Ahmed Luqmani
Funding Agency and Grant Number
Corresponding Author	Cristina Ponte, MD, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Oxford OX3 7LD, United Kingdom. cristinadbponte@gmail.com
Key Words	Giant cell arteritis; Therapy; Disease mana­gement; Glucocorticoids; Immunosuppressive agents
Core Tip	Giant cell arteritis (GCA) is the most common form of primary systemic vasculitis. Treatment with high doses of glucocorticoids should be initiated as early as possible to prevent ischaemic manifestations, such as blindness (occurring in up to 20%). However, glucocorticoid therapy leads to significant toxicity in over 80% of the patients. Various steroid-sparing agents have been tried, but robust scientific evidence of their efficacy and safety is still lacking. Not all patients follow the same course, but there are no valid biomarkers to assess therapy response. The authors review the optimal strategies for treatment and monitoring of patients with GCA.
Publish Date	2015-06-19 16:35
Citation	Ponte C, Rodrigues AF, O’Neill L, Luqmani RA. Giant cell arteritis: Current treatment and management. World J Clin Cases 2015; 3(6): 484-494
URL	http://www.wjgnet.com/2307-8960/full/v3/i6/484.htm
DOI	http://dx.doi.org/10.12998/wjcc.v3.i6.484

Full Article (PDF)	WJCC-3-484.pdf
Full Article (Word)	WJCC-3-484.doc
Manuscript File	16226-Review.docx
Answering Reviewers	16226-Answering reviewers.pdf
Audio Core Tip	16226-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	16226-Conflict-of-interest statement.pdf
Copyright License Agreement	16226-Copyright assignment.pdf
Peer-review Report	16226-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16226-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16226-Scientific misconduct check.pdf
Scientific Editor Work List	16226-Scientific editor work list.pdf