BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
11/27/2015 2:50:00 PM | Browse: 980 | Download: 1285
Publication Name World Journal of Stem Cells
Manuscript ID 16540
Country/Territory United States
Received
2015-01-22 08:53
Peer-Review Started
2015-01-22 14:05
To Make the First Decision
2015-03-06 10:14
Return for Revision
2015-03-15 15:23
Revised
2015-04-02 09:21
Second Decision
2015-09-29 17:25
Accepted by Journal Editor-in-Chief
2015-09-30 08:53
Accepted by Company Editor-in-Chief
2015-10-13 17:28
Articles in Press
2015-10-13 17:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-11-04 18:34
Publish the Manuscript Online
2015-11-27 14:51
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Dedifferentiated fat cells: A cell source for regenerative medicine
Manuscript Source Invited Manuscript
All Author List Medet Jumabay and Kristina I Boström
Funding Agency and Grant Number
Funding Agency Grant Number
American Heart Association to Medet Jumabay
NIH P01 HL30568(to Kristina I Boström)
NIH R01 HL81397(to Kristina I Boström)
NIH R01 HL112839 (to Kristina I Boström)
Corresponding Author Medet Jumabay, MD, PhD, Division of Cardiology, David Geffen School of Medicine at UCLA, Box 951679, Los Angeles, CA 90095-1679, United States. mjumabay@mednet.ucla.edu
Key Words Adipocytes; Dedifferentiated fat cells; Adult stem cells; Pluripotent stem cells; Differentiation
Core Tip Multipotent dedifferentiated fat (DFAT) cells provide evidence of plasticity in adipocytes. The newly established DFAT cells exhibit vigorous proliferation and multipotent abilities with advantages over other adult stem cells. Modified culture methods reduce the risk of contamination by cells from the stromal vascular fraction to a minimum. In in vitro and/or in vivo experiments have revealed adipogenic, osteogenic, chondrogenic, myogenic, angiogenic and neourogenic potentials in DFAT cells. Moreover, the DFAT cells express embryonic stem cell markers and are similar to induced pluripotent stem cells in certain physiological aspects. Based on the abundance, ease of preparation, homogeneity, and multi-lineage potential, the DFAT cells are uniquely suited for regenerative medicine.
Publish Date 2015-11-27 14:51
Citation Jumabay M, Boström KI. Dedifferentiated fat cells: A cell source for regenerative medicine. World J Stem Cells 2015; 7(10): 1202-1214
URL http://www.wjgnet.com/1948-0210/full/v7/i10/1202.htm
DOI http://dx.doi.org/10.4252/wjsc.v7.i10.1202
Full Article (PDF) WJSC-7-1202.pdf
Full Article (Word) WJSC-7-1202.doc
Manuscript File 16540-Review.docx
Answering Reviewers 16540-Answering reviewers.pdf
Audio Core Tip 16540-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 16540-Conflict-of-interest statement.pdf
Copyright License Agreement 16540-Copyright assignment.pdf
Peer-review Report 16540-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16540-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16540-Scientific misconduct check.pdf
Scientific Editor Work List 16540-Scientific editor work list.pdf