ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Comparison of gastric mucosa in Mongolian and Japanese patients with reference to gastric cancer and Helicobacter pylori infection
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Takeshi Matsuhisa, Yoshio Yamaoka, Tomohisa Uchida, Davaadorj Duger, Battulga Adiyasuren, Oyuntsetseg Khasag, Tserentogtokh Tegshee and Byambajav Tsogt-Ochir |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Institutes of Health |
DK62813(in part) |
Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan |
24406015 |
Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan |
24659200 |
Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan |
25293104 |
Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan |
26640114 |
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Corresponding Author |
Takeshi Matsuhisa, MD, Professor, Department of Gastroenterology, Tama-Nagayama University Hospital, Nippon Medical School, Tama, Tokyo 206-8512, Japan. matuhisa@nms.ac.jp
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Key Words |
Gastric cancer; Helicobacter pylori; Non-East Asian-type strain; Chronic inflammation; Neutrophile activity; Glandular atrophy; Intestinal metaplasia; Mongolians; Japanese |
Core Tip |
Characteristics of gastric cancer and gastric mucosa in Mongolian patients were observed. Approximatery half of the Mongolian cancers were located in the upper part of the stomach. The infection rate of Helicobacter pylori (H. pylori) was higher in Mongolians than Japanese (75.9% and 48.3%, respectively, P < 0.0001). Mongolians were infected with non-East Asian-type H. pylori strains. Both atrophic score and intestinal metaplasia score were lower in H. pylori infected Mongolians than in Japanese (P < 0.0001). The type of gastritis changed from antrum-predominant gastritis to corpus-predominant gastritis with age in both populations.
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Publish Date |
2015-07-22 13:58 |
Citation |
Matsuhisa T, Yamaoka Y, Uchida T, Duger D, Adiyasuren B, Khasag O, Tegshee T, Tsogt-Ochir B. Gastric mucosa in Mongolian and Japanese patients with gastric cancer and Helicobacter pylori infection. World J Gastroenterol 2015; 21(27): 8408-8417 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i27/8408.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i27.8408 |