Publication Name	World Journal of Gastroenterology
Manuscript ID	1767
Country	Japan

Received	2013-01-05 10:22
Peer-Review Started	2013-01-05 13:54
To Make the First Decision	2013-02-01 21:51
Return for Revision	2013-02-03 18:12
Revised	2013-02-10 22:16
Second Decision	2013-04-28 14:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-04-29 01:04
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-05-30 01:26
Typeset the Manuscript	2013-06-13 20:04
Publish the Manuscript Online	2013-06-28 23:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Active treatments are a rational approach for hepatocellular carcinoma in elderly patients
Manuscript Source	Invited Manuscript
All Author List	Takeshi Suda, Aiko Nagashima, Shyunsaku Takahashi, Tsutomu Kanefuji, Kenya Kamimura, Yasushi Tamura, Masaaki Takamura, Masato Igarashi, Hirokazu Kawai, Satoshi Yamagiwa, Minoru Nomoto and Yutaka Aoyagi
Funding Agency and Grant Number
Corresponding Author	Dr. Takeshi Suda, Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Niigata 951-8122, Japan. suda@med.niigata-u.ac.jp
Key Words	Hepatocellular carcinoma; Population aging; Survival; Life expectancy; Active intervention
Core Tip	Progressive population aging worldwide demands consensus development for decision making to treat elderly patients. A simple comparison of survival days is confounded by aging; therefore, age compensation is mandatory to evaluate survival benefits among different age groups. In this study, age difference was compensated by life expectancy in a hepatocellular carcinoma cohort. The authors suggested that age itself might not be a critical determinant for the selection of a therapeutic option. This study emphasizes the importance of clarifying risk determinants specific for elderly patients with respect to individual aspects and medical economy.
Publish Date	2013-06-28 23:55
Citation	Suda T, Nagashima A, Takahashi S, Kanefuji T, Kamimura K, Tamura Y, Takamura M, Igarashi M, Kawai H, Yamagiwa S, Nomoto M, Aoyagi Y. Active treatments are a rational approach for hepatocellular carcinoma in elderly patients. World J Gastroenterol 2013; 19(24): 3831-3840
URL	http://www.wjgnet.com/1007-9327/full/v19/i24/3831.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i24.3831

Full Article (PDF)	WJG-19-3831.pdf
Manuscript File	1767-Review.docx
Answering Reviewers	1767-Answering reviewers.doc
Copyright License Agreement	1767-Copyright assignment.pdf
Peer-review Report	1767-Peer review(s).pdf
Scientific Editor Work List	1767-Scientific editor work list.doc