Publication Name	World Journal of Hepatology
Manuscript ID	18134
Country	Greece

Received	2015-04-08 08:21
Peer-Review Started	2015-04-09 22:26
To Make the First Decision	2015-04-27 15:41
Return for Revision	2015-04-28 15:56
Revised	2015-05-25 01:04
Second Decision	2015-07-02 09:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-07-14 09:53
Articles in Press	2015-07-14 09:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-14 17:29
Publish the Manuscript Online	2015-07-24 19:52

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Circulating biomarkers of hepatocellular carcinoma response after locoregional treatments: New insights
Manuscript Source	Invited Manuscript
All Author List	Maria Tampaki, Polyxeni P Doumba, Melanie Deutsch and John Koskinas
Funding Agency and Grant Number
Corresponding Author	John Koskinas, MD, PhD, Academic Department of Medicine, Medical School of Athens, Hippokration General Hospital, Vas. Sofias 114, 11527 Athens, Greece. koskinasj@yahoo.gr
Key Words	Radiofrequency ablation; Transarterial chemoembolization; Hepatocellular cancer; Circulating biomarkers; Prognosis
Core Tip	Hepatocellular cancer is the 5th most common cancer in the world and the third cause of death by malignant disease. Locoregional therapies are available for patients with early or intermediate stage of disease. However even with these techniques recurrence rates are high. The use of accurate prognostic biomarkers is of great importance in order to select the most suitable-personalised treatment. The aim of this review is to analyze the existing data regarding circulating biomarkers measured before and after locoregional therapies and their effect on treatment outcome.
Publish Date	2015-07-24 19:52
Citation	Tampaki M, Doumba PP, Deutsch M, Koskinas J. Circulating biomarkers of hepatocellular carcinoma response after locoregional treatments: New insights. World J Hepatol 2015; 7(14): 1834-1842
URL	http://www.wjgnet.com/1948-5182/full/v7/i14/1834.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i14.1834

Full Article (PDF)	WJH-7-1834.pdf
Full Article (Word)	WJH-7-1834.doc
Manuscript File	18134-Review.docx
Answering Reviewers	18134-Answering reviewers.pdf
Audio Core Tip	18134-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	18134-Conflict-of-interest statement.pdf
Copyright License Agreement	18134-Copyright assignment.pdf
Peer-review Report	18134-Peer-review(s).pdf
Scientific Misconduct Check	18134-Scientific misconduct check.pdf
Scientific Editor Work List	18134-Scientific editor work list .pdf