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Articles Published Processes
1/20/2016 5:04:00 PM | Browse: 950 | Download: 1182
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Received |
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2015-05-14 09:15 |
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Peer-Review Started |
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2015-05-15 15:17 |
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To Make the First Decision |
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2015-08-31 08:30 |
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Return for Revision |
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2015-09-29 16:06 |
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Revised |
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2015-10-11 01:11 |
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Second Decision |
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2015-11-03 09:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2015-11-13 16:01 |
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Articles in Press |
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2015-11-13 16:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-01-05 12:25 |
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Publish the Manuscript Online |
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2016-01-20 16:55 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Gut epithelial barrier dysfunction in human immunodeficiency virus-hepatitis C virus coinfected patients: Influence on innate and acquired immunity
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mercedes Márquez, Clotilde Fernández Gutiérrez del Álamo and José Antonio Girón-González |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Instituto de Salud Carlos III, Plan Nacional de I+D+I 2008-2011 |
PI11/00605 |
| Instituto de Salud Carlos III, Plan Estatal de I+D+I 2013-2016 |
PI14/01779 |
| FEDER (Fondo Europeo de Desarrollo Regional) |
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| Corresponding Author |
José Antonio Girón-González, MD, PhD, Department of Internal Medicine, Infectious Disease Unit, Puerta del Mar University Hospital, University of Cadiz, Avda Ana de Viya 21, 11009 Cádiz, Spain. joseantonio.giron@uca.es
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| Key Words |
Human immunodeficiency virus infection; Hepatitis C virus infection; Innate immunity; Acquired immunity; Gut barrier |
| Core Tip |
Even in patients with a long-term controlled human immunodeficiency virus (HIV) replication by antiretroviral therapy, HIV-infected patients have several non-acquired immunodeficiency virus (AIDS) related co-morbidities, including liver disease. Persistent innate and acquired immune activation contributes to the pathogenesis of these non-AIDS related diseases. Immune activation has been related with bacterial translocation secondary to gut barrier damage by the HIV or the hepatitis C virus (HCV)-related liver cirrhosis. Modifications in gut barrier structure and function and immune activation in HIV-HCV coinfected patients will be reviewed.
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| Publish Date |
2016-01-20 16:55 |
| Citation |
Márquez M, Fernández Gutiérrez del Álamo C, Girón-González JA. Gut epithelial barrier dysfunction in human immunodeficiency virus-hepatitis C virus coinfected patients: Influence on innate and acquired immunity. World J Gastroenterol 2016; 22(4): 1433-1448 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i4/1433.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i4.1433 |
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