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Publication Name World Journal of Gastroenterology
Manuscript ID 19604
Country/Territory Spain
Received
2015-05-14 09:15
Peer-Review Started
2015-05-15 15:17
To Make the First Decision
2015-08-31 08:30
Return for Revision
2015-09-29 16:06
Revised
2015-10-11 01:11
Second Decision
2015-11-03 09:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-11-13 16:01
Articles in Press
2015-11-13 16:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-01-05 12:25
Publish the Manuscript Online
2016-01-20 16:55
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Gut epithelial barrier dysfunction in human immunodeficiency virus-hepatitis C virus coinfected patients: Influence on innate and acquired immunity
Manuscript Source Invited Manuscript
All Author List Mercedes Márquez, Clotilde Fernández Gutiérrez del Álamo and José Antonio Girón-González
Funding Agency and Grant Number
Funding Agency Grant Number
Instituto de Salud Carlos III, Plan Nacional de I+D+I 2008-2011 PI11/00605
Instituto de Salud Carlos III, Plan Estatal de I+D+I 2013-2016 PI14/01779
FEDER (Fondo Europeo de Desarrollo Regional)
Corresponding Author José Antonio Girón-González, MD, PhD, Department of Internal Medicine, Infectious Disease Unit, Puerta del Mar University Hospital, University of Cadiz, Avda Ana de Viya 21, 11009 Cádiz, Spain. joseantonio.giron@uca.es
Key Words Human immunodeficiency virus infection; Hepatitis C virus infection; Innate immunity; Acquired immunity; Gut barrier
Core Tip Even in patients with a long-term controlled human immunodeficiency virus (HIV) replication by antiretroviral therapy, HIV-infected patients have several non-acquired immunodeficiency virus (AIDS) related co-morbidities, including liver disease. Persistent innate and acquired immune activation contributes to the pathogenesis of these non-AIDS related diseases. Immune activation has been related with bacterial translocation secondary to gut barrier damage by the HIV or the hepatitis C virus (HCV)-related liver cirrhosis. Modifications in gut barrier structure and function and immune activation in HIV-HCV coinfected patients will be reviewed.
Publish Date 2016-01-20 16:55
Citation Márquez M, Fernández Gutiérrez del Álamo C, Girón-González JA. Gut epithelial barrier dysfunction in human immunodeficiency virus-hepatitis C virus coinfected patients: Influence on innate and acquired immunity. World J Gastroenterol 2016; 22(4): 1433-1448
URL http://www.wjgnet.com/1007-9327/full/v22/i4/1433.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i4.1433
Full Article (PDF) WJG-22-1433.pdf
Full Article (Word) WJG-22-1433.doc
Manuscript File 19604-Review.docx
Answering Reviewers 19604-Answering reviewers.pdf
Audio Core Tip 19604-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 19604-Conflict-of-interest statement.pdf
Copyright License Agreement 19604-Copyright assignment.pdf
Institutional Review Board Approval Form or Document Institutional_Review_Board_Statement_20150514005902.pdf
Non-Native Speakers of English Editing Certificate 19604-Language certificate.pdf
Peer-review Report 19604-Peer-review(s).pdf
Scientific Misconduct Check 19604-Scientific misconduct check.pdf
Scientific Editor Work List 19604-Scientific editor work list.pdf