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Publication Name World Journal of Gastroenterology
Manuscript ID 20133
Country Italy
2015-05-29 10:20
Peer-Review Started
2015-06-01 08:34
To Make the First Decision
2015-07-14 11:48
Return for Revision
2015-07-24 16:47
2015-08-06 22:01
Second Decision
2015-10-10 18:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-10-13 18:27
Articles in Press
2015-10-13 18:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-01-05 17:54
Publish the Manuscript Online
2016-01-20 16:55
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Topic Highlights
Article Title Significance of hepatitis virus infection in the oncogenic initiation of hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Caecilia HC Sukowati, Korri E El-Khobar, Susan I Ie, Beatrice Anfuso, David H Muljono and Claudio Tiribelli
Funding Agency and Grant Number
Corresponding Author Caecilia HC Sukowati, PhD, Fondazione Italiana Fegato ONLUS, AREA Science Park Basovizza, SS14 km 163.5, 34149 Trieste, Italy. caecilia.sukowati@csf.units.it
Key Words Hepatocellular carcinoma; Hepatitis B virus; Hepatitis C virus; Oncogenicity; Viral pathogenicity
Core Tip According to the most recent data released by the International Agency for Research on Cancer-World Health Organization, liver cancer is the second most common cause of cancer mortality worldwide. Hepatocellular carcinoma (HCC) accounts for around 90% of liver cancer cases and it is variably distributed according to its main risk factors. The hepatotropic viral [hepatitis B virus (HBV) and hepatitis C virus (HCV)] infection can cause a disarrangement in cellular pathways through an indirect and/or direct mechanism in liver injury. This review summarize available data in literature regarding the oncogenic properties of HBV and HCV in the initiation of HCC, including their role in the activation of hepatic stem cells.
Publish Date 2016-01-20 16:55
Citation Sukowati CHC, El-Khobar KE, Ie SI, Anfuso B, Muljono DH, Tiribelli C. Significance of hepatitis virus infection in the oncogenic initiation of hepatocellular carcinoma. World J Gastroenterol 2016; 22(4): 1497-1512
URL http://www.wjgnet.com/1007-9327/full/v22/i4/1497.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i4.1497
Full Article (PDF) WJG-22-1497.pdf
Full Article (Word) WJG-22-1497.doc
Manuscript File 20133-Review.docx
Answering Reviewers 20133-Answering reviewers.pdf
Audio Core Tip 20133-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 20133-Conflict-of-interest statement.pdf
Copyright License Agreement 20133-Copyright assignment.pdf
Peer-review Report 20133-Peer-review(s).pdf
Scientific Misconduct Check 20133-Scientific misconduct check.pdf
Scientific Editor Work List 20133-Scientific editor work list.pdf