Publication Name	World Journal of Hepatology
Manuscript ID	20990
Country	Japan

Received	2015-06-27 19:43
Peer-Review Started	2015-06-30 08:50
To Make the First Decision	2015-08-16 17:02
Return for Revision	2015-08-20 18:26
Revised	2015-08-28 12:31
Second Decision	2015-10-19 19:17
Accepted by Journal Editor-in-Chief	2015-10-21 11:22
Accepted by Company Editor-in-Chief	2015-11-04 17:24
Articles in Press	2015-11-04 17:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-10 17:35
Publish the Manuscript Online	2015-11-18 11:12

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Factors associated with the response to interferon-based antiviral therapies for chronic hepatitis C
Manuscript Source	Invited Manuscript
All Author List	Hirayuki Enomoto and Shuhei Nishiguchi
Funding Agency and Grant Number
Corresponding Author	Hirayuki Enomoto, MD, PhD, Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa-cho 1-1, Nishinomiya, Hyogo 663-8501, Japan. enomoto@hyo-med.ac.jp
Key Words	Anti-interferon-α neutralizing antibody; Interferon-α; Direct-acting antiviral; Interferon-free treatment; Chronic hepatitis C
Core Tip	Interferon-α (IFN-α) therapy has been playing a central role in anti-hepatitis C virus (HCV) strategies, and several viral and host factors related to the treatment efficacy have been identified. After the development of pegylated-IFN-α (Peg-IFN-α), the clinical impact of anti-IFN-α neutralizing antibodies in the treatment for HCV infection has not been sufficiently addressed. We recently found that anti-IFN-α neutra-lizing antibodies were associated with a non-response to Peg-IFN-α treatment. Our findings provide important information for the treatment of chronic hepatitis C in the clinical setting.
Publish Date	2015-11-18 11:12
Citation	Enomoto H, Nishiguchi S. Factors associated with the response to interferon-based antiviral therapies for chronic hepatitis C. World J Hepatol 2015; 7(26): 2681-2687
URL	http://www.wjgnet.com/1948-5182/full/v7/i26/2681.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i26.2681

Full Article (PDF)	WJH-7-2681.pdf
Full Article (Word)	WJH-7-2681.doc
Manuscript File	20990-Review.docx
Answering Reviewers	20990-Answering reviewers.pdf
Audio Core Tip	20990-Audio core tip.wma
Conflict-of-Interest Disclosure Form	20990-Conflict-of-interest statement.pdf
Copyright License Agreement	20990-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	20990-Language certificate.pdf
Peer-review Report	20990-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20990-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20990-Scientific misconduct check.pdf
Scientific Editor Work List	20990-Scientific editor work list.pdf