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11/27/2015 4:41:00 PM | Browse: 737 | Download: 698
Publication Name World Journal of Immunology
Manuscript ID 21656
Country/Territory United Kingdom
Received
2015-07-24 09:26
Peer-Review Started
2015-07-27 15:18
To Make the First Decision
2015-08-16 14:56
Return for Revision
2015-08-25 19:32
Revised
2015-09-18 23:44
Second Decision
2015-11-02 14:24
Accepted by Journal Editor-in-Chief
2015-11-05 07:36
Accepted by Company Editor-in-Chief
2015-11-11 18:11
Articles in Press
2015-11-11 18:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-11-16 09:02
Publish the Manuscript Online
2015-11-27 16:41
ISSN 2219-2824 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Review
Article Title Dendritic cells and the extracellular matrix: A challenge for maintaining tolerance/homeostasis
Manuscript Source Invited Manuscript
All Author List Sucharita P Shankar, May Griffith, John V Forrester and Lucia Kuffová
Funding Agency and Grant Number
Corresponding Author Dr. Lucia Kuffová, MD, PhD, Section of Immunology, Inflammation and Infection, Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen, Scotland AB25 2ZD, United Kingdom. l.kuffova@abdn.ac.uk
Key Words Dendritic cells; Extracellular matrix; Tolerance; Biomaterials; Homeostasis; Regenerative medicine; Biointeractive implants
Core Tip The extracellular matrix (ECM) provides an essential framework for tissues in the body as well as actively orchestrates diverse cellular functions. Professional antigen presenting cells namely dendritic cells (DCs) are uniquely positioned to distinguish between self and non-self and accordingly regulate systemic immunity or tolerance. DCs and the ECM participate in finely-tuned, dynamic exchanges that ultimately impact the equilibrium between steady-state DC tissue residence or DC-instigated inflammation. To design biointeractive, ECM-inspired implants for regenerative medicine applications that retain functionality and undergo successful integration long-term, it is critical to understand the challenges involved in maintaining DC-ECM immune homeostasis under normal conditions.
Publish Date 2015-11-27 16:41
Citation Shankar SP, Griffith M, Forrester JV, Kuffová L. Dendritic cells and the extracellular matrix: A challenge for maintaining tolerance/homeostasis. World J Immunol 2015; 5(3): 113-130
URL http://www.wjgnet.com/2219-2824/full/v5/i3/113.htm
DOI http://dx.doi.org/10.5411/wji.v5.i3.113
Full Article (PDF) WJI-5-113.pdf
Full Article (Word) WJI-5-113.doc
Manuscript File 21656-Review.docx
Answering Reviewers 21656-Answering reviewers.pdf
Audio Core Tip 21656-Audio core tip.wav
Conflict-of-Interest Disclosure Form 21656-Conflict-of-interest statement.pdf
Copyright License Agreement 21656-Copyright assignment.pdf
Peer-review Report 21656-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 21656-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 21656-Scientific misconduct check.pdf
Scientific Editor Work List 21656-Scientific editor work list.pdf