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3/28/2016 3:05:00 PM | Browse: 546 | Download: 622
Publication Name World Journal of Gastroenterology
Manuscript ID 23878
Country/Territory China
2015-12-22 09:15
Peer-Review Started
2015-12-22 15:34
To Make the First Decision
2016-01-28 14:37
Return for Revision
2016-01-28 15:56
2016-02-12 02:05
Second Decision
2016-02-19 09:22
Accepted by Journal Editor-in-Chief
2016-02-19 15:47
Accepted by Company Editor-in-Chief
2016-03-02 08:16
Articles in Press
2016-03-02 08:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-03-14 10:11
Publish the Manuscript Online
2016-03-28 15:05
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Minireviews
Article Title Liver cancer stem cell markers: Progression and therapeutic implications
Manuscript Source Invited Manuscript
All Author List Jing-Hui Sun, Qing Luo, Ling-Ling Liu and Guan-Bin Song
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 11272365
Corresponding Author Guan-bin Song, PhD, Professor of Biomedical Engineering, Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, No.174, Shapingba Street, Shapingba District, Chongqing 400044, China. song@cqu.edu.cn
Key Words Liver cancer; Cancer recurrence; Liver cancer stem cells; Cancer stem cell markers; Targeted therapy
Core Tip Liver cancer is the fifth most common cancer and the third leading cause of cancer-related mortality worldwide despite remarkable progress in understanding hepatocarcinogenesis and new therapeutic approaches. Recently, the presence of highly resistant cancer stem cells (CSCs) in liver cancer has been proposed to be responsible for tumor growth, invasion, metastasis and recurrence. CSC involvement in liver cancer pathogenesis also highlights them as preferential targets for therapy. This review specifically focuses on the markers used to define human liver cancer stem cells, the therapeutic implications of the expression of these markers in patient’s primary tumors, and the potential of the markers to serve as therapeutic targets.
Publish Date 2016-03-28 15:05
Citation Sun JH, Luo Q, Liu LL, Song GB. Liver cancer stem cell markers: Progression and therapeutic implications. World J Gastroenterol 2016; 22(13): 3547-3557
Url http://www.wjgnet.com/1007-9327/full/v22/i13/3547.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i13.3547
Full Article (PDF) WJG-22-3547.pdf
Full Article (Word) WJG-22-3547.doc
Manuscript File 23878-Review.docx
Answering Reviewers 23878-Answering reviewers.pdf
Audio Core Tip 23878-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 23878-Conflict-of-interest statement.pdf
Copyright License Agreement 23878-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 23878-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 23878-Language certificate.pdf
Peer-review Report 23878-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 23878-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 23878-Scientific misconduct check.pdf
Scientific Editor Work List 23878-Scientific editor work list.pdf