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3/30/2016 3:59:00 PM | Browse: 728 | Download: 713
Publication Name World Journal of Hepatology
Manuscript ID 24432
Country/Territory United Kingdom
Received
2016-01-22 09:29
Peer-Review Started
2016-01-23 08:47
To Make the First Decision
2016-02-22 10:21
Return for Revision
2016-02-22 14:30
Revised
2016-03-02 02:28
Second Decision
2016-03-07 15:35
Accepted by Journal Editor-in-Chief
2016-03-09 16:31
Accepted by Company Editor-in-Chief
2016-03-16 16:09
Articles in Press
2016-03-16 16:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-03-24 16:47
Publish the Manuscript Online
2016-03-30 15:59
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Hepatocellular carcinoma: Review of disease and tumor biomarkers
Manuscript Source Invited Manuscript
All Author List Jin Un Kim, Mohamed I F Shariff, Mary M E Crossey, Maria Gomez-Romero, Elaine Holmes, I Jane Cox, Haddy K S Fye, Ramou Njie and Simon D Taylor-Robinson
Funding Agency and Grant Number
Corresponding author Jin Un Kim, BSc, Division of Digestive Health, Department of Surgery and Cancer, Imperial College London, St Mary’s Campus, South Wharf Road, London W2 1NY, United Kingdom. juk11@ic.ac.uk
Key Words Hepatocellular carcinoma; Biomarker; Metabonomics; Warburg hypothesis; Serum; Plasma; Urine
Core Tip Many independent authors have utilized quan-titative techniques, such as 1H nuclear magnetic resonance and mass spectrometry to discover novel biomarkers to aid early diagnosis, following the removal of alpha fetoprotein from international surveillance guidelines. However, relatively little effort has been directed to translate these findings to the clinical setting. hepatocellular carcinoma (HCC) is a global issue and the vast majority of the burden is placed upon resource-limited regions, where presentations are late and management techniques for advanced tumors are unavailable. Early identification through a simple serum or urinary investigation, therefore, may be a pivotal step in addressing the global burden of HCC.
Publish Date 2016-03-30 15:59
Citation Kim JU, Shariff MIF, Crossey MME, Gomez-Romero M, Holmes E, Cox IJ, Fye HKS, Njie R, Taylor-Robinson SD. Hepatocellular carcinoma: Review of disease and tumor biomarkers. World J Hepatol 2016; 8(10): 471-484
Url http://www.wjgnet.com/1948-5182/full/v8/i10/471.htm
DOI http://dx.doi.org/10.4254/wjh.v8.i10.471
Full Article (PDF) WJH-8-471.pdf
Full Article (Word) WJH-8-471.doc
Manuscript File 24432-Review.docx
Answering Reviewers 24432-Answering reviewers.pdf
Audio Core Tip 24432-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 24432-Conflict-of-interest statement.pdf
Copyright License Agreement 24432-Copyright assignment.pdf
Peer-review Report 24432-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 24432-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 24432-Scientific misconduct check.pdf
Scientific Editor Work List 24432-Scientific editor work list.pdf