ISSN |
1948-9366 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Surgery |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Incidental non-benign gallbladder histopathology after cholecystectomy in an United Kingdom population: Need for routine histological analysis?
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Manuscript Source |
Invited Manuscript |
All Author List |
Krashna Patel, Khaled Dajani, Satheesh Iype, Nikolaos A Chatzizacharias, Saranya Vickramarajah, Prateush Singh, Susan Davies, Rebecca Brais, Siong S Liau, Simon Harper, Asif Jah, Raaj K Praseedom and Emmanuel L Huguet |
Funding Agency and Grant Number |
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Corresponding Author |
Emmanuel L Huguet, MD, PhD, Consultant Hepato-Pancreato-Biliary surgeon, Department of Surgery, Hepato-Pancreato-Biliary Unit, Addenbrooke’s Hospital, Hills Road, Cambridge CB20XZ, United Kingdom. emmanuel.huguet@addenbrookes.nhs.uk |
Key Words |
Gallbladder; Incidental; Cholecystectomy; Histopathology; Carcinoma |
Core Tip |
The selective use of histopahological examination of gallbladders removed during routine cholecystectomy has been advocated by several authors in the literature. We present a large single centre study demonstrating a full range of gallbladder disease from cholecystectomy specimens, including more than 1% neoplastic histology and two cases of microscopic gallbladder malignancies in macroscopically normal gallbladders. On this basis, routine histological evaluation of all elective and emergency cholecystectomies is justified in an United Kingdom population as selective analysis has potential to miss potentially curable life threatening pathology. |
Publish Date |
2016-10-25 16:05 |
Citation |
Patel K, Dajani K, Iype S, Chatzizacharias NA, Vickramarajah S, Singh P, Davies S, Brais R, Liau SS, Harper S, Jah A, Praseedom RK, Huguet EL. Incidental non-benign gallbladder histopathology after cholecystectomy in an United Kingdom population: Need for routine histological analysis? World J Gastrointest Surg 2016; 8(10): 685-692 |
URL |
http://www.wjgnet.com/1948-9366/full/v8/i10/685.htm |
DOI |
http://dx.doi.org/10.4240/wjgs.v8.i10.685 |