Publication Name	World Journal of Gastroenterology
Manuscript ID	27629
Country	United States

Received	2016-06-08 10:16
Peer-Review Started	2016-06-13 18:38
To Make the First Decision	2016-10-20 13:13
Return for Revision	2016-10-20 16:21
Revised	2016-11-18 09:24
Second Decision	2016-12-02 08:16
Accepted by Journal Editor-in-Chief	2016-12-04 11:50
Accepted by Company Editor-in-Chief	2016-12-08 16:13
Articles in Press	2016-12-08 16:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-22 21:37
Publish the Manuscript Online	2017-01-05 11:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Minireviews
Article Title	Neutropenic enterocolitis
Manuscript Source	Invited Manuscript
All Author List	Fabio G Rodrigues, Giovanna Dasilva and Steven D Wexner
Funding Agency and Grant Number
Corresponding Author	Steven D Wexner, MD, PhD (Hon), Department of Colorectal Surgery, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd, Weston, FL 33331, United States. wexners@ccf.org
Key Words	Neutropenic enterocolitis; Neutropenic colitis; Immunocompromise; Intestinal mucosal injury; Neutropenia; Intestinal edema; Intramural invasion; Pathogenesis
Core Tip	Neutropenic colitis is a severe condition usually affecting immunocompromised patients. Its exact pathogenesis is not completely understood. The main elements in disease onset appear to be intestinal mucosal injury together with neutropenia and the weakened immune system of the afflicted patients. These initial conditions lead to intestinal edema, engorged vessels, and a disrupted mucosal surface, which becomes more vulnerable to bacterial intramural invasion. Chemotherapeutic agents can cause direct mucosal injury or can predispose to distension and necrosis, thereby altering intestinal motility.
Publish Date	2017-01-05 11:10
Citation	Rodrigues FG, Dasilva G, Wexner SD. Neutropenic enterocolitis. World J Gastroenterol 2017; 23(1): 42-47
URL	http://www.wjgnet.com/1007-9327/full/v23/i1/42.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i1.42

Full Article (PDF)	WJG-23-42.pdf
Full Article (Word)	WJG-23-42.doc
Manuscript File	27629-Review.docx
Answering Reviewers	27629-Answering reviewers.pdf
Audio Core Tip	27629-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	27629-Conflict-of-interest statement.pdf
Copyright License Agreement	27629-Copyright assignment.pdf
Peer-review Report	27629-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	27629-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	27629-Scientific misconduct check.pdf
Scientific Editor Work List	27629-Scientific editor work list.pdf