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12/19/2016 8:28:00 PM | Browse: 867 | Download: 1151
Publication Name World Journal of Gastroenterology
Manuscript ID 29101
Country/Territory Spain
Received
2016-08-10 09:35
Peer-Review Started
2016-08-11 10:13
To Make the First Decision
2016-09-05 14:46
Return for Revision
2016-09-08 11:46
Revised
2016-09-25 03:56
Second Decision
2016-10-24 16:46
Accepted by Journal Editor-in-Chief
2016-10-24 21:43
Accepted by Company Editor-in-Chief
2016-10-31 15:19
Articles in Press
2016-10-31 15:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-11-12 12:18
Typeset the Manuscript
2016-12-07 16:32
Publish the Manuscript Online
2016-12-19 20:29
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Observational Study
Article Title Short-term effectiveness of golimumab for ulcerative colitis: Observational multicenter study
Manuscript Source Invited Manuscript
All Author List Marta Maia Bosca-Watts, Xavier Cortes, Marisa Iborra, Jose Maria Huguet, Laura Sempere, Gloria Garcia, Rafa Gil, MariFe Garcia, Marga Muñoz, Pedro Almela, Nuria Maroto and Jose Maria Paredes
Funding Agency and Grant Number
Corresponding Author Marta Maia Bosca-Watts, PhD, MD, Inflammatory Bowel Disease Unit, Digestive Disease Department, University of Valencia, University Clinic Hospital of Valencia, Avda. Blasco Ibañez 17, 46010 Valencia, Spain. inflamatoriahcuv@gmail.com
Key Words Golimumab; Ulcerative colitis; Real-life results
Core Tip Golimumab is a fully humanized anti-tumor necrosis factor-alpha (anti-TNF) monoclonal antibody, which has recently been accepted in clinical practice. Pivotal studies have demonstrated the drug’s benefits, but real-life studies are still scarce. This observational, prospective and multi-center study in moderate-severe ulcerative colitis patients, confirmed golimumab’s short-term (14 wk) effectiveness. A high percentage of patients had responded and were off steroids at the end of follow-up. No severe adverse events were observed. Intensification (reducing the drug administration interval or increasing the dosage) may be useful in many slow-to-respond cases.
Publish Date 2016-12-19 20:29
Citation Bosca-Watts MM, Cortes X, Iborra M, Huguet JM, Sempere L, Garcia G, Gil R, Garcia M, Muñoz M, Almela P, Maroto N, Paredes JM. Short-term effectiveness of golimumab for ulcerative colitis: Observational multicenter study. World J Gastroenterol 2016; 22(47): 10432-10439
URL http://www.wjgnet.com/1007-9327/full/v22/i47/10432.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i47.10432
Full Article (PDF) WJG-22-10432.pdf
Full Article (Word) WJG-22-10432.doc
Manuscript File 29101-Review.docx
Answering Reviewers 29101-Answering reviewers.pdf
Audio Core Tip 29101-Audio core tip.m4a
Biostatistics Review Certificate 29101-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 29101-Conflict-of-interest statement.pdf
Copyright License Agreement 29101-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 29101-Institutional review board statement.pdf
Peer-review Report 29101-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 29101-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 29101-Scientific misconduct check.pdf
Scientific Editor Work List 29101-Scientific editor work list.pdf