Publication Name	World Journal of Gastroenterology
Manuscript ID	29124
Country	Italy

Received	2016-07-29 09:07
Peer-Review Started	2016-08-02 20:26
To Make the First Decision	2016-09-28 08:37
Return for Revision	2016-09-30 11:00
Revised	2016-10-13 21:59
Second Decision	2016-11-11 14:24
Accepted by Journal Editor-in-Chief	2016-11-14 00:47
Accepted by Company Editor-in-Chief	2016-11-16 13:01
Articles in Press	2016-11-16 13:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-11-23 19:10
Publish the Manuscript Online	2016-12-06 17:24

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Gastrointestinal neuromuscular apparatus: An underestimated target of gut microbiota
Manuscript Source	Invited Manuscript
All Author List	Michele Pier Luca Guarino, Michele Cicala, Lorenza Putignani and Carola Severi
Funding Agency and Grant Number
Corresponding Author	Michele Pier Luca Guarino, MD, PhD, Digestive Disease Unit of Campus Bio Medico University of Rome, Via Alvaro del Portillo 200, 00128 Rome, Italy. m.guarino@unicampus.it
Key Words	Microbiota; Gastrointestinal motility; Smooth muscle; Enteric nervous system; Probiotics; Irritable bowel syndrome
Core Tip	This article reviews the current evidence of gut microbiota and neuromuscular apparatus connection that results to be both direct and indirect. Besides dysbiosis-driven mucosal inflammatory mediators, recent evidence suggests that gut neuromuscular apparatus can be modulated directly by microbiota metabolic products or circulating bacterial molecular components translocated from the intestinal lumen.
Publish Date	2016-12-06 17:24
Citation	Guarino MPL, Cicala M, Putignani L, Severi C. Gastrointestinal neuromuscular apparatus: An underestimated target of gut microbiota. World J Gastroenterol 2016; 22(45): 9871-9879
URL	http://www.wjgnet.com/1007-9327/full/v22/i45/9871.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i45.9871

Full Article (PDF)	WJG-22-9871.pdf
Full Article (Word)	WJG-22-9871.doc
Manuscript File	29124-Review.docx
Answering Reviewers	29124-Answering reviewers.pdf
Audio Core Tip	29124-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29124-Conflict-of-interest statement.pdf
Copyright License Agreement	29124-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	29124-Language certificate.pdf
Peer-review Report	29124-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	29124-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	29124-Scientific misconduct check.pdf
Scientific Editor Work List	29124-Scientific editor work list.pdf