Publication Name	World Journal of Gastroenterology
Manuscript ID	31686
Country	China

Received	2016-12-02 09:33
Peer-Review Started	2016-12-02 11:01
To Make the First Decision	2016-12-28 16:55
Return for Revision	2017-01-03 08:08
Revised	2017-02-15 16:00
Second Decision	2017-03-01 11:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-03-02 16:59
Articles in Press	2017-03-02 16:59
Publication Fee Transferred
Edit the Manuscript by Language Editor	2017-03-31 22:40
Typeset the Manuscript	2017-04-10 18:06
Publish the Manuscript Online	2017-04-28 10:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Study of the effects of nesfatin-1 on gastric function in obese rats
Manuscript Source	Unsolicited Manuscript
All Author List	Guo-Tao Yang, Hong-Ying Zhao, Yu Kong, Ning-Ning Sun and Ai-Qin Dong
Funding Agency and Grant Number	Funding Agency Grant Number Cangzhou City Science and Technology Plan Projects 151302138
Corresponding Author	Dr. Guo-Tao Yang, Department of Third Neurology, Cangzhou Central Hospital, Cangzhou Clinical Medical School of Hebei Medical University, Cangzhou 061001, Hebei Province, China. yangguotaotao@yeah.net
Key Words	Obesity; Nesfatin-1; H+/K+-ATPase
Core Tip	The high-fat diet-induced obese rat model was used to study the effects of nesfatin-1 on gastric function. We found that intracerebroventricular injection of nesfatin-1, rather than intravenous injection, could suppress gastric function in a dose-dependent manner within a certain period of time. In addition, the expression of H+/K+ ATPase was down-regulated, which may explain the mechanisms of gastric acid secretion changes.
Publish Date	2017-04-28 10:26
Citation	Yang GT, Zhao HY, Kong Y, Sun NN, Dong AQ. Study of the effects of nesfatin-1 on gastric function in obese rats. World J Gastroenterol 2017; 23(16): 2940-2947
URL	http://www.wjgnet.com/1007-9327/full/v23/i16/2940.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i16.2940

Full Article (PDF)	WJG-23-2940.pdf
Full Article (Word)	WJG-23-2940.doc
Manuscript File	31686-Review.docx
Answering Reviewers	31686-Answering reviewers.pdf
Audio Core Tip	31686-Audio core tip.mp3
Biostatistics Review Certificate	31686-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	31686-Conflict-of-interest statement.pdf
Copyright License Agreement	31686-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	31686-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20161201195725.doc
Institutional Animal Care and Use Committee Approval Form or Document	Institutional_Animal_Care_and_Use_Committee_Statement_20161201195732.doc
Institutional Review Board Approval Form or Document	31686-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	31686-Language certificate.pdf
Peer-review Report	31686-Peer-review(s).pdf
Scientific Misconduct Check	31686-Scientific misconduct check.pdf
Scientific Editor Work List	31686-Scientific editor work list.pdf