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6/14/2017 7:52:42 AM | Browse: 192 | Download: 111
Publication Name World Journal of Hepatology
Manuscript ID 33809
Country of Manuscript Source Turkey
Received
2017-03-05 17:41
Peer-Review Started
2017-03-07 16:51
To Make the First Decision
2017-04-17 09:16
Return for Revision
2017-04-18 15:13
Revised
2017-04-24 23:06
Second Decision
2017-05-11 13:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-05-19 05:44
Articles in Press
2017-05-19 05:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-05-31 08:03
Publish the Manuscript Online
2017-06-14 07:52
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Review
Article Title Liver immunology and herbal treatment
Manuscript Source Invited Manuscript
All Author List Yasemin H Balaban, Ceylan Aka and Ufuk Koca-Caliskan
Funding Agency and Grant Number
Correspondence To Dr. Yasemin H Balaban, Professor, Gastroenterology Unit, Private Etimed Hospital, Elvan Mah, 1934 Sok, No. 4, 06790 Ankara, Turkey. ybalaban@hacettepe.edu.tr
Keywords Herbal treatments; Hepatic immunology; Drug induced liver injury; Adaptive immunity; Innate immunity
Core Tip Herbal treatment is the mother of modern medicine. The ancient habit of treating diseases with plants still goes on as either primary or complementary to conventional medical treatment. The other side of medallion is the fact that the liver is number one target organ for herbal toxicity. Furthermore, liver has been recently defined as an active organ of immune system, which have central regulatory role on innate and adaptive immune response. The delicate homeostasis between immediate and efficient defense against threats (immune surveilance of antigens) without triggering harmful immune response towards self-structures (periferal immune tolerance to self antigens) is controled by liver. Herbal formulas are not a single plant extract, but is an interacting mixture of ingredients that determines the final clinical outcome as therapeutic and hepatotoxic effect. This review aimed to drive attention on both potentials of herbals from the point of immunology, in order to initiate a motivation for feature studies defining the mechanisms of immunological interaction between herbals and liver.
Publish Date 2017-06-14 07:52
Citation Balaban YH, Aka C, Koca-Caliskan U. Liver immunology and herbal treatment. World J Hepatol 2017; 9(17): 757-770
Url http://www.wjgnet.com/1948-5182/full/v9/i17/757.htm
DOI http://dx.doi.org/10.4254/wjh.v9.i17.757
Full Article (PDF) WJH-9-757.pdf
Full Article (Word) WJH-9-757.doc
Manuscript File 33809-Review.doc
Answering Reviewers 33809-Answering reviewers.pdf
Audio Core Tip 33809-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 33809-Conflict-of-interest statement.pdf
Copyright License Agreement 33809-Copyright assignment.pdf
Peer-review Report 33809-Peer-review(s).pdf
Scientific Misconduct Check 33809-Scientific misconduct check.pdf
Scientific Editor Work List 33809-Scientific editor work list.pdf