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9/14/2017 3:13:08 AM | Browse: 347 | Download: 299
Publication Name World Journal of Gastroenterology
Manuscript ID 34915
Country of Manuscript Source China
2017-06-07 00:27
Peer-Review Started
2017-06-08 07:06
To Make the First Decision
2017-07-13 05:02
Return for Revision
2017-07-17 11:55
2017-07-29 12:28
Second Decision
2017-08-15 07:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-08-15 15:12
Articles in Press
2017-08-15 15:12
Publication Fee Transferred
2017-08-22 02:48
Edit the Manuscript by Language Editor
2017-08-26 07:36
Typeset the Manuscript
2017-09-07 02:41
Publish the Manuscript Online
2017-09-14 03:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Infectious Diseases
Manuscript Type Basic Study
Article Title Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation
Manuscript Source Unsolicited Manuscript
All Author List Zhi-Qiang Wei, Yong-Hong Zhang, Chang-Zheng Ke, Hong-Xia Chen, Pan Ren, Yu-Lin He, Pei Hu, De-Qiang Ma, Jie Luo and Zhong-Ji Meng
Author(s) ORCID Number
Zhi-Qiang Wei http://orcid.org/0000-0002-6067-589X
Yong-Hong Zhang http://orcid.org/0000-0002-5741-9406
Chang-Zheng Ke http://orcid.org/0000-0002-9766-7420
Hong-Xia Chen http://orcid.org/0000-0003-2331-0880
Pan Ren http://orcid.org/0000-0001-5445-433X
Yu-Lin He http://orcid.org/0000-0002-4728-523X
Pei Hu http://orcid.org/0000-0003-0116-7737
De-Qiang Ma http://orcid.org/0000-0003-3657-7576
Jie Luo http://orcid.org/0000-0002-6043-472X
Zhong-Ji Meng http://orcid.org/0000-0003-0401-535X
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81541140
Natural Science Foundation of the Hubei Province of China 2014CFB645
Research and Development Project of the Science and Technology Plan of Hubei Province 2011BCB030
Foundation for Innovative Research Team of Hubei University of Medicine 2014CXG05
Key Program for Precision Medicine of Taihe Hospital 2016JZ05
Corresponding author Zhong-Ji Meng, MD, Professor, Institute of Biomedical Research, Taihe Hospital, Hubei University of Medicine, South Renmin Road No. 32, Shiyan 442000, Hubei Province, China. zhongji.meng@taihehospital.com
Keywords Curcumin; Hepatitis B virus; Covalently closed circular DNA; Histone deacetylation
Core Tip We showed that curcumin inhibited hepatitis B virus (HBV) replication and expression via reductions in covalently closed circular DNA-bound histone acety­lation. Furthermore, siRNAs targeting HBV acted synergistically with curcumin, resulting in enhanced inhibition of HBV.
Publish Date 2017-09-14 03:13
Citation Wei ZQ, Zhang YH, Ke CZ, Chen HX, Ren P, He YL, Hu P, Ma DQ, Luo J, Meng ZJ. Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation. World J Gastroenterol 2017; 23(34): 6252-6260
Url http://www.wjgnet.com/1007-9327/full/v23/i34/6252.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i34.6252
Full Article (PDF) WJG-23-6252.pdf
Full Article (Word) WJG-23-6252.doc
Manuscript File 34915-Review.docx
Answering Reviewers 34915-Answering reviewers.pdf
Audio Core Tip 34915-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 34915-Conflict-of-interest statement.pdf
Copyright License Agreement 34915-Copyright assignment.pdf
Data Sharing Statement 34915-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 34915-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 34915-Language certificate.pdf
Scientific Research Process 34915-Scientific research process.pdf
Supplementary Material 34915-Supplementary-Material-revision.docx
Peer-review Report 34915-Peer-review(s).pdf
Scientific Misconduct Check 34915-Scientific misconduct check.pdf
Scientific Editor Work List 34915-Scientific editor work list.pdf