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11/12/2017 6:39:43 AM | Browse: 715 | Download: 1125
Publication Name World Journal of Gastroenterology
Manuscript ID 34921
Country/Territory Japan
Received
2017-06-29 01:17
Peer-Review Started
2017-06-30 08:38
To Make the First Decision
2017-07-27 07:56
Return for Revision
2017-08-01 11:25
Revised
2017-09-08 15:59
Second Decision
2017-09-15 00:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-09-19 21:01
Articles in Press
2017-09-19 21:01
Publication Fee Transferred
2017-09-27 12:40
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-11-06 04:39
Publish the Manuscript Online
2017-11-12 06:39
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Nuclear heat shock protein 110 expression is associated with poor prognosis and hyperthermo-chemotherapy resistance in gastric cancer patients with peritoneal metastasis
Manuscript Source Unsolicited Manuscript
All Author List Akiharu Kimura, Kyoichi Ogata, Bolag Altan, Takehiko Yokobori, Erito Mochiki, Mitsuhiro Yanai, Norimichi Kogure, Toru Yanoma, Masaki Suzuki, Tuya Bai and Hiroyuki Kuwano
ORCID
Author(s) ORCID Number
Akiharu Kimura http://orcid.org/0000-0002-6832-4146
Kyoichi Ogata http://orcid.org/0000-0001-8059-159X
Bolag Altan http://orcid.org/0000-0002-2222-0966
Takehiko Yokobori http://orcid.org/0000-0003-3284-4796
Erito Mochiki http://orcid.org/0000-0001-5991-4913
Mitsuhiro Yanai http://orcid.org/0000-0002-2627-5665
Norimichi Kogure http://orcid.org/0000-0001-5046-8742
Toru Yanoma http://orcid.org/0000-0003-2513-6521
Masaki Suzuki http://orcid.org/0000-0002-1503-6861
Tuya Bai http://orcid.org/0000-0003-4815-5450
Hiroyuki Kuwano http://orcid.org/0000-0003-1809-8483
Funding Agency and Grant Number
Corresponding Author Akiharu Kimura, MD, PhD, Senior Lecturer, Department of General Surgical Science, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan. akimura@gunma-u.ac.jp
Key Words Peritoneal metastasis; Hyperthermia; Hyperthermo-chemotherapy; Heat shock protein 110; Gastric cancer; Drug resistance
Core Tip Gastric cancer remains one of the most common cancers worldwide. Peritoneal dissemination is the most common reason behind gastric cancer (GC) recurrence, and the median survival duration for patients with metastatic and recurrent GC is only 13–16 mo. In our department, we have used intraperitoneal hyperthermo-chemotherapy in patients with advanced rectal cancer and GC with peritoneal metastasis. In this study, we evaluated the significance of heat shock protein 110 (HSP110) expression in GC patients with peritoneal metastasis and assessed the effects of HSP110 suppression on hyperthermo-chemotherapy sensitivity in vitro.
Publish Date 2017-11-12 06:39
Citation Kimura A, Ogata K, Altan B, Yokobori T, Mochiki E, Yanai M, Kogure N, Yanoma T, Suzuki M, Bai T, Kuwano H. Nuclear heat shock protein 110 expression is associated with poor prognosis and hyperthermo-chemotherapy resistance in gastric cancer patients with peritoneal metastasis. World J Gastroenterol 2017; 23(42): 7541-7550
URL http://www.wjgnet.com/1007-9327/full/v23/i42/7541.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i42.7541
Full Article (PDF) WJG-23-7541.pdf
Full Article (Word) WJG-23-7541.doc
Manuscript File 34921-Review.docx
Answering Reviewers 34921-Answering reviewers.pdf
Audio Core Tip 34921-Audio core tip.mp3
Biostatistics Review Certificate 34921-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 34921-Conflict-of-interest statement.pdf
Copyright License Agreement 34921-Copyright assignment.pdf
Data Sharing Statement 34921-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 34921-Approved-Grant-Application-Form(s)-or-Funding-Agency-Copy-of-any-Approval-Document(s).doc
Institutional Animal Care and Use Committee Approval Form or Document 34921-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 34921-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 34921-Non-Native-Speakers-of-English-revision.pdf
Scientific Research Process 34921-Scientific-Research-Process-revision.doc
Peer-review Report 34921-Peer-review(s).pdf
Scientific Misconduct Check 34921-Scientific misconduct check.pdf
Scientific Editor Work List 34921-Scientific editor work list.pdf