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2/9/2018 7:24:29 AM | Browse: 386 | Download: 186
Publication Name World Journal of Gastroenterology
Manuscript ID 37031
Country/Territory Australia
Received
2017-11-06 08:59
Peer-Review Started
2017-11-07 09:42
To Make the First Decision
2017-11-30 06:03
Return for Revision
2017-12-01 09:20
Revised
2017-12-11 01:59
Second Decision
2017-12-19 11:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-12-20 02:18
Articles in Press
2017-12-20 02:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-02-08 08:03
Publish the Manuscript Online
2018-02-09 07:24
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer
Manuscript Source Unsolicited Manuscript
All Author List Daniel Brungs, David Lynch, Alison WS Luk, Elahe Minae, Marie Ranson, Morteza Aghmesheh, Kara L Vine, Martin Carolan, Mouhannad Jaber, Paul de Souza and Therese Becker
ORCID
Author(s) ORCID Number
Daniel Brungs http://orcid.org/0000-0002-8154-6966
David Lynch http://orcid.org/0000-0002-9589-4478
Alison WS Luk http://orcid.org/0000-0003-1221-7023
Elahe Minae http://orcid.org/0000-0002-8674-6801
Marie Ranson http://orcid.org/0000-0002-5570-9645
Morteza Aghmesheh http://orcid.org/0000-0003-1664-4743
Kara L Vine http://orcid.org/0000-0001-6871-1149
Martin Carolan http://orcid.org/0000-0001-6671-029X
Mouhannad Jaber http://orcid.org/0000-0001-6991-9507
Paul de Souza http://orcid.org/0000-0002-7380-1170
Therese Becker http://orcid.org/0000-0002-5636-9902
Funding Agency and Grant Number
Corresponding author Daniel Brungs, BSc, MBBS, Doctor, Illawarra Cancer Care Centre, Wollongong Hospital, Crown St, Wollongong 2500, Australia. daniel.brungs@health.nsw.gov.au
Keywords Cryopreservation; Circulating tumor cells; Liquid biopsy; Gastroesophageal cancer; Gastric cancer
Core Tip This study demonstrates a novel and robust protocol for the cryopreservation and thawing of patient blood samples, demonstrating reliable circulating tumor cell isolation and characterisation after the long term storage of patient samples. Using the largest patient cohort reported to date, we validated our method by confirming the independent prognostic association of circulating tumor cell (CTC) enumeration from cryopre­served peripheral blood mononuclear cells. Cryopre­servation may assist with the wider incorporation of CTC collection and analysis in biobanking, retrospec­tive studies, and large international clinical trials, by facilitating specimen storage, bulk transporting, and batch processing.
Publish Date 2018-02-09 07:24
Citation Brungs D, Lynch D, Luk AW, Minaei E, Ranson M, Aghmesheh M, Vine KL, Carolan M, Jaber M, de Souza P, Becker TM. Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer. World J Gastroenterol 2018; 24(7): 810-818
Url http://www.wjgnet.com/1007-9327/full/v24/i7/810.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i7.810
Full Article (PDF) WJG-24-810.pdf
Full Article (Word) WJG-24-810.doc
Manuscript File 37031-Review.docx
Answering Reviewers 37031-Answering reviewers.pdf
Audio Core Tip 37031-Audio core tip.m4a
Biostatistics Review Certificate 37031-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 37031-Conflict-of-interest statement.pdf
Copyright License Agreement 37031-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 37031-Institutional review board statement.pdf
Supplementary Material 37031-Supplementary material.pdf
Peer-review Report 37031-Peer-review(s).pdf
Scientific Misconduct Check 37031-Scientific misconduct check.pdf
Scientific Editor Work List 37031-Scientific editor work list.pdf