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1/26/2018 8:09:36 AM | Browse: 461 | Download: 269
Publication Name World Journal of Hepatology
Manuscript ID 37063
Country/Territory Spain
2017-11-09 14:31
Peer-Review Started
2017-11-10 06:37
To Make the First Decision
2017-12-01 07:23
Return for Revision
2017-12-04 03:30
2017-12-21 09:13
Second Decision
2018-01-12 08:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-01-15 22:24
Articles in Press
2018-01-15 22:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-01-25 03:14
Publish the Manuscript Online
2018-01-26 08:09
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Role of inflammatory response in liver diseases: Therapeutic strategies
Manuscript Source Invited Manuscript
All Author List Jose A Del Campo, Paloma Gallego and Lourdes Grande
Author(s) ORCID Number
Jose A Del Campo http://orcid.org/0000-0002-6037-1028
Paloma Gallego http://orcid.org/0000-0002-7233-0127
Lourdes Grande http://orcid.org/0000-0001-7685-0464
Funding Agency and Grant Number
Funding Agency Grant Number
Insituto de Salud Carlos III PI14/01349
Consejería de Salud, Junta de Andalucía PI0892-2012
Corresponding author Jose A Del Campo, PhD, Senior Scientist, Department of Digestive Diseases, Valme University Hospital, Avda. Bellvista s/n, Sevilla 41014, Spain. jantonio.delcampo@ciberehd.org
Keywords Caspase-1; Fibrosis; Hepatitis C virus; Inflammasome; Interleukin-1α; Interleukin-1β; Liver disease; Non-alcoholic fatty liver disease; NLRP3; Tumor necrosis factor-alpha
Core Tip Inflammasomes are newly recognized vital players in innate immunity. Several factors have been identified able to activate the NLRP3 inflammasome. Inappropriate activation of NLRP3 can contribute to the onset and progression of various diseases, particularly age-related diseases. It is well established that hepatitis C virus infection plays a critical role in the promotion of liver inflammation and disease, inducing the production of IL-1β and the activation of NLRP3. NLRP3 inflammasome gain of function aggravates liver disease, resulting in severe liver fibrosis and lately, hepatocellular carcinoma. In non-alcoholic fatty liver disease, the regulation of inflammation processes may prevent the progression of non-alcoholic steatohepatitis to fibrosis.
Publish Date 2018-01-26 08:09
Citation Del Campo JA, Gallego P, Grande L. Role of inflammatory response in liver diseases: Therapeutic strategies. World J Hepatol 2018; 10(1): 1-7
Url http://www.wjgnet.com/1948-5182/full/v10/i1/1.htm
DOI http://dx.doi.org/10.4254/wjh.v10.i1.1
Full Article (PDF) WJH-10-1.pdf
Full Article (Word) WJH-10-1.doc
Manuscript File 37063-Review.doc
Answering Reviewers 37063-Answering reviewers.pdf
Audio Core Tip 37063-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 37063-Conflict-of-interest statement.pdf
Copyright License Agreement 37063-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 37063-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 37063-Non-Native Speakers of English Editing Certificate.pdf
Peer-review Report 37063-Peer-review(s).pdf
Scientific Misconduct Check 37063-Scientific misconduct check.pdf
Scientific Editor Work List 37063-Scientific editor work list.pdf