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4/4/2018 1:15:45 PM | Browse: 994 | Download: 2208
Publication Name World Journal of Gastroenterology
Manuscript ID 38485
Country/Territory Japan
Received
2018-02-25 02:04
Peer-Review Started
2018-02-25 11:47
To Make the First Decision
2018-03-08 01:06
Return for Revision
2018-03-09 07:33
Revised
2018-03-13 15:32
Second Decision
2018-03-16 09:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-03-18 01:37
Articles in Press
2018-03-18 01:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-04-03 05:46
Publish the Manuscript Online
2018-04-04 13:15
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Helicobacter pylori infection in subjects negative for high titer serum antibody
Manuscript Source Unsolicited Manuscript
All Author List Osamu Toyoshima, Toshihiro Nishizawa, Masahide Arita, Yosuke Kataoka, Kosuke Sakitani, Shuntaro Yoshida, Hiroharu Yamashita, Keisuke Hata, Hidenobu Watanabe and Hidekazu Suzuki
ORCID
Author(s) ORCID Number
Osamu Toyoshima http://orcid.org/0000-0002-6953-6079
Toshihiro Nishizawa http://orcid.org/0000-0003-4876-3384
Masahide Arita http://orcid.org/0000-0003-1952-8086
Yosuke Kataoka http://orcid.org/0000-0002-8374-6558
Kosuke Sakitani http://orcid.org/0000-0002-4537-6023
Shuntaro Yoshida http://orcid.org/0000-0002-9437-9132
Hiroharu Yamashita http://orcid.org/0000-0002-9468-3716
Keisuke Hata http://orcid.org/0000-0003-4064-8701
Hidenobu Watanabe http://orcid.org/0000-0002-7871-4738
Hidekazu Suzuki http://orcid.org/0000-0002-3855-3140
Funding Agency and Grant Number
Corresponding Author Osamu Toyoshima, MD, Doctor, Department of Gastroenterology, Toyoshima Endoscopy Clinic, 6-17-5 Seijo, Setagaya-ku, Tokyo 1570066, No, Japan. t@ichou.com
Key Words Kyoto classification; Gastritis; Helicobacter pylori; Antibody; Endoscopy
Core Tip Compared with negative-low titer (< 3 U/mL on E-plate Eiken kit), negative-high titer (3-9.9 U/mL) have been reported to be at higher risk for intestinal gastric cancer. Helicobacter pylori (H. pylori)-infected patients accounted for 94% of gastric cancer patients with an antibody titer of < 10 U/mL. Seventeen percent of subjects with negative-high titer serum anti-H. pylori antibody tested positive for H. pylori infection. Endoscopic Kyoto classification of gastritis was an excellent predictor of H. pylori infection with large area under the receiver operating characteristics curve (0.886), cut-off value of 2, and high accuracy (89.7%), indicating its high confidence.
Publish Date 2018-04-04 13:15
Citation Toyoshima O, Nishizawa T, Arita M, Kataoka Y, Sakitani K, Yoshida S, Yamashita H, Hata K, Watanabe H, Suzuki H. Helicobacter pylori infection in subjects negative for high titer serum antibody. World J Gastroenterol 2018; 24(13): 1419-1428
URL http://www.wjgnet.com/1007-9327/full/v24/i13/1419.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i13.1419
Full Article (PDF) WJG-24-1419.pdf
Full Article (Word) WJG-24-1419.doc
STROBE Statement 38485-STROBE statement.pdf
Manuscript File 38485-Review.docx
Answering Reviewers 38485-Answering reviewers.pdf
Audio Core Tip 38485-Audio core tip.mp3
Biostatistics Review Certificate 38485-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 38485-Conflict-of-interest statement.pdf
Copyright License Agreement 38485-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 38485-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 38485-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 38485-Language certificate.pdf
Peer-review Report 38485-Peer-review(s).pdf
Scientific Misconduct Check 38485-Scientific misconduct check.pdf
Scientific Editor Work List 38485-Scientific editor work list.pdf