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Articles Published Processes
9/15/2018 11:10:20 AM | Browse: 988 | Download: 1103
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Received |
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2018-04-16 02:03 |
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Peer-Review Started |
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2018-04-16 11:50 |
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To Make the First Decision |
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2018-05-02 03:41 |
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Return for Revision |
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2018-05-03 06:15 |
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Revised |
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2018-06-05 14:57 |
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Second Decision |
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2018-06-27 08:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-06-28 16:25 |
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Articles in Press |
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2018-06-28 16:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-07-09 16:27 |
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Typeset the Manuscript |
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2018-09-14 01:13 |
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Publish the Manuscript Online |
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2018-09-15 11:10 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Colorectal carcinogenesis: Insights into the cell death and signal transduction pathways: A review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ashok Kumar Pandurangan, Thomas Divya, Kalaivani Kumar, Vadivel Dineshbabu, Bakthavatchalam Velavan and Ganapasam Sudhandiran |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ganapasam Sudhandiran, MPhil, MSc, PhD, Associate Professor, Cell Biology Laboratory, Department of Biochemistry, University of Madras, Guindy Campus, Chennai 600025, India. sudhandiran@yahoo.com |
| Key Words |
Colorectal cancer; Cell death; Apoptosis; Autophagy; Inflammation; Hippo signalling; Nuclear factor erythroid 2-related factor 2; Wnt signaling |
| Core Tip |
Colorectal carcinogenesis (CRC) imposes a major health burden. This review addresses the cell death mechanisms and major signal transduction pathways involved in CRC. Regulated cell death is important for maintaining normal homeostasis, and the dysregulation of cell death processes leads to a spectrum of diseases including cancer. It is interesting to note that cell death pathways collaborate with each other, so understanding the various cell death mechanisms are therefore essential. CRC is orchestrated by various signal transduction pathways, which are used as drug targets. This review highlights the key concepts concerning cell death mechanisms and signal transduction in CRC. |
| Publish Date |
2018-09-15 11:10 |
| Citation |
Pandurangan AK, Divya T, Kumar K, Dineshbabu V, Velavan B, Sudhandiran G. Colorectal carcinogenesis: Insights into the cell death and signal transduction pathways: A review. World J Gastrointest Oncol 2018; 10(9): 244-259 |
| URL |
http://www.wjgnet.com/1948-5204/full/v10/i9/244.htm |
| DOI |
http://dx.doi.org/10.4251/wjgo.v10.i9.244 |
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