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12/21/2018 10:07:20 AM | Browse: 789 | Download: 1119
Publication Name World Journal of Gastroenterology
Manuscript ID 40145
Country/Territory Israel
Received
2018-08-10 05:34
Peer-Review Started
2018-08-10 05:43
To Make the First Decision
2018-10-24 01:50
Return for Revision
2018-10-24 08:17
Revised
2018-11-26 09:17
Second Decision
2018-12-06 10:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-07 03:33
Articles in Press
2018-12-07 03:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-12-20 08:31
Publish the Manuscript Online
2018-12-21 10:07
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Five years of fecal microbiota transplantation - an update of the Israeli experience
Manuscript Source Unsolicited Manuscript
All Author List Sharon A Greenberg, Ilan Youngster, Nathaniel A Cohen, Dan M Livovsky, Jacob Strahilevitz, Eran Israeli, Ehud Melzer, Kalman Paz, Naomi Fliss-Isakov and Nitsan Maharshak
ORCID
Author(s) ORCID Number
Sharon A Greenberg http://orcid.org/0000-0001-7346-1746
Ilan Youngster http://orcid.org/0000-0001-5233-1213
Nathaniel A Cohen http://orcid.org/0000-0002-3997-4174
Dan M Livovsky http://orcid.org/0000-0002-8212-9638
Jacob Strahilevitz http://orcid.org/0000-0002-9192-7164
Eran Israeli http://orcid.org/0000-0001-8679-4363
Ehud Melzer http://orcid.org/0000-0002-3021-6684
Kalman Paz http://orcid.org/0000-0001-5357-1593
Naomi Fliss-Isakov http://orcid.org/0000-0003-4849-0291
Nitsan Maharshak http://orcid.org/0000-0002-9324-0024
Funding Agency and Grant Number
Corresponding Author Nitsan Maharshak, MD, Chief Doctor, Director, Doctor, Senior Lecturer, Department of Gastroenterology and Liver Diseases & Bacteriotherapy Clinic, Tel Aviv Sourasky Medical Center, 6 Weizmann St., Tel Aviv 6423906, Israel. nitsanm@tlvmc.gov.il
Key Words Clostridium difficile infection; Capsules; Israel; Fecal microbiota transplantation
Core Tip Fecal microbiota transplantation (FMT) emerged as a promising treatment for Clostridium difficile infection (CDI). Our aim was to summarize the national Israeli experience in FMT. One-hundred and eleven patients with CDI underwent FMT, 37 (35%) of which via oral capsules and 50 (45%) via colonoscopy. The overall success rate was 87.4%, with no difference between administration routes. Success was independently related to mild disease and an ambulatory setting. One-third of the patients were younger than 60 years. 14 of which (40%) also suffered from inflammatory bowel disease. FMT is an effective treatment for recurrent CDI. FMT via capsules was shown to be a successful alternative to endoscopy.
Publish Date 2018-12-21 10:07
Citation Greenberg SA, Youngster I, Cohen NA, Livovsky DM, Strahilevitz J, Israeli E, Melzer E, Paz K, Fliss-Isakov N, Maharshak N. Five years of fecal microbiota transplantation - an update of the Israeli experience. World J Gastroenterol 2018; 24(47): 5403-5414
URL https://www.wjgnet.com/1007-9327/full/v24/i47/5403.htm
DOI https://dx.doi.org/10.3748/wjg.v24.i47.5403
Full Article (PDF) WJG-24-5403.pdf
Full Article (Word) WJG-24-5403.doc
STROBE Statement 40145-STROBE statement.pdf
Manuscript File 40145-Review.docx
Answering Reviewers 40145-Answering reviewers.pdf
Audio Core Tip 40145-Audio core tip.mp3
Biostatistics Review Certificate 40145-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 40145-Conflict-of-interest statement.pdf
Copyright License Agreement 40145-Copyright license agreement.PDF
Signed Informed Consent Form(s) or Document(s) 40145-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 40145-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 40145-Language certificate.pdf
Peer-review Report 40145-Peer-review(s).pdf
Scientific Misconduct Check 40145-Scientific misconduct check.pdf
Scientific Editor Work List 40145-Scientific editor work list.pdf