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11/26/2018 6:01:26 AM | Browse: 596 | Download: 765
Publication Name World Journal of Stem Cells
Manuscript ID 41840
Country/Territory Switzerland
2018-08-30 06:08
Peer-Review Started
2018-08-30 08:38
To Make the First Decision
2018-10-17 01:51
Return for Revision
2018-10-17 06:52
2018-10-18 08:01
Second Decision
2018-10-23 02:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-10-23 21:59
Articles in Press
2018-10-23 21:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-10-30 21:19
Typeset the Manuscript
2018-11-20 13:55
Publish the Manuscript Online
2018-11-26 06:01
ISSN 1948-0210 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Minireviews
Article Title Single-cell analysis of tumors: Creating new value for molecular biomarker discovery of cancer stem cells and tumor-infiltrating immune cells
Manuscript Source Invited Manuscript
All Author List Ramin Radpour and Farzad Forouharkhou
Author(s) ORCID Number
Ramin Radpour http://orcid.org/0000-0002-5632-7833
Farzad Forouharkhou http://orcid.org/0000-0002-6249-6115
Funding Agency and Grant Number
Corresponding Author Ramin Radpour, MSc, PhD, Senior Researcher, Tumor Immunology, Department for BioMedical Research (DBMR), University of Bern, Murtenstrasse 35, Bern 3008, Switzerland. ramin.radpour@dbmr.unibe.ch
Key Words Cancer cells; Cancer stem cells; Cancer biomarkers; Tumor-infiltrating lymphocytes; Single-cell analysis
Core Tip Extensive heterogeneity in cancer cells ne­gatively influences treatment efficacy and survival of patients. The existing molecular methods for biomar­ker discovery of cancer cells and cancer stem cells are often unsuited to capture the heterogeneous nature of cell populations. Recent advances in single-cell based profiling approaches allowed the detection of molecular changes in individual cancer cells. Therefore, single-cell analysis is leading to build a complete landscape of cell types within tumor cells and facilitating the study of complex molecular heterogeneity in cancer cell po­pulations. This will improve the investigation of more specific biomarkers to identify and target cancer stem cells.
Publish Date 2018-11-26 06:01
Citation Radpour R, Forouharkhou F. Single-cell analysis of tumor cells: Creating new value for molecular biomarker discovery of cancer stem cells. World J Stem Cells 2018; 10(11): 160-171
URL http://www.wjgnet.com/1948-0210/full/v10/i11/160.htm
DOI http://dx.doi.org/10.4252/wjsc.v10.i11.160
Full Article (PDF) WJSC-10-160.pdf
Full Article (Word) WJSC-10-160.doc
Manuscript File 41840-Review.docx
Answering Reviewers 41840-Answering reviewers.pdf
Audio Core Tip 41840-Audio core tipn.mp3
Conflict-of-Interest Disclosure Form 41840-Conflict-of-interest statement.pdf
Copyright License Agreement 41840-Copyright license agreement.pdf
Peer-review Report 41840-Peer-review(s).pdf
Scientific Misconduct Check 41840-Scientific misconduct check.pdf
Scientific Editor Work List 41840-Scientific editor work list.pdf