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2/26/2019 3:18:49 AM | Browse: 115 | Download: 53
Publication Name World Journal of Stem Cells
Manuscript ID 42749
Country of Manuscript Source China
Received
2018-10-09 10:07
Peer-Review Started
2018-10-10 01:25
To Make the First Decision
2018-11-29 07:49
Return for Revision
2018-12-06 07:28
Revised
2018-12-30 08:57
Second Decision
2019-01-22 01:26
Accepted by Journal Editor-in-Chief
2019-01-22 01:28
Accepted by Company Editor-in-Chief
2019-01-23 16:00
Articles in Press
2019-01-23 16:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-02-02 21:47
Typeset the Manuscript
2019-02-25 10:20
Publish the Manuscript Online
2019-02-26 03:18
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Cell Biology
Manuscript Type Review
Article Title Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders
Manuscript Source Unsolicited Manuscript
All Author List Qiang Liu, Mo-Xian Chen, Lin Sun, Chloe U Wallis, Jian-Song Zhou, Li-Juan Ao, Qi Li and Pak C Sham
ORCID
Author(s) ORCID Number
Qiang Liu http://orcid.org/0000-0002-0167-2963
Mo-Xian Chen http://orcid.org/0000-0001-6019-5776
Lin Sun http://orcid.org/0000-0001-7496-7685
Chloe U Wallis http://orcid.org/0000-0002-6770-8324
Jian-Song Zhou http://orcid.org/0000-0002-4410-4202
Li-Juan Ao http://orcid.org/0000-0002-5116-1993
Qi Li http://orcid.org/0000-0002-3732-2578
Pak C Sham http://orcid.org/0000-0002-2533-7270
Funding Agency and Grant Number
Funding Agency Grant Number
National Nature Science Foundation of China 81660381
Corresponding author Qi Li, PhD, Postdoctoral Fellow, Department of Psychiatry, the University of Hong Kong, 21 Sasson Roads, Pokfulam, Hong Kong , China. liqihku@gmail.com
Keywords Autism spectrum disorders; Mesenchymal stem cells; Major histocompatibility complex; Inflammation; Maternal immune activation; Cell therapy
Core Tip Autism spectrum disorder (ASD) is a complex, behaviorally defined disorder characterised by severe impairments in social communication and repetitive behavior. Because of an incomplete understanding of the pathology of ASD, available options of treatments in ASD are only symptomatic. We discuss the role of immune dysfunction in the etiology of ASD and function of mesenchymal stem cells (MSCs). We summerize the pre-clinical and clinical evidence for MSC therapy in ASD and suggest that more basic experiments are needed to better understanding of the therapeutic mechanisms of MSCs in ASD.
Publish Date 2019-02-26 03:18
Citation Liu Q, Chen MX, Sun L, Wallis CU, Zhou JS, Ao LJ, Li Q, Sham PC. Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders. World J Stem Cells 2019; 11(2): 55-72
Url https://www.wjgnet.com/1948-0210/full/v11/i2/55.htm
DOI https://dx.doi.org/10.4252/wjsc.v11.i2.55
Full Article (PDF) WJSC-11-55.pdf
Full Article (Word) WJSC-11-55.docx
Manuscript File FP6768_de16_CE1MS_edit2.docx
Answering Reviewers 42749-Answering reviewers.pdf
Audio Core Tip 42749-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 42749-Conflict-of-interest statement.pdf
Copyright License Agreement 42749-Copyright license agreement.pdf
Peer-review Report 42749-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 42749-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 42749-Scientific misconduct check.pdf
Scientific Editor Work List 42749-Scientific editor work list.pdf