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1/7/2019 10:39:41 AM | Browse: 26 | Download: 62
Publication Name World Journal of Gastroenterology
Manuscript ID 42853
Country of Manuscript Source Japan
2018-10-19 01:32
Peer-Review Started
2018-10-19 03:58
To Make the First Decision
2018-12-05 06:10
Return for Revision
2018-12-05 08:29
2018-12-12 14:56
Second Decision
2018-12-19 09:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-20 01:40
Articles in Press
2018-12-20 01:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-06 10:19
Publish the Manuscript Online
2019-01-07 10:39
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Usefulness of urinary trypsinogen-2 and trypsinogen activation peptide in acute pancreatitis: A multicenter study in Japan
Manuscript Source Unsolicited Manuscript
All Author List Hiroaki Yasuda, Keisho Kataoka, Yoshifumi Takeyama, Kazunori Takeda, Tetsuhide Ito, Toshihiko Mayumi, Shuji Isaji, Tetsuya Mine, Motoji Kitagawa, Seiki Kiriyama, Junichi Sakagami, Atsushi Masamune, Kazuo Inui, Kenji Hirano, Ryukichi Akashi, Masamichi Yokoe, Yoshio Sogame, Kazuichi Okazaki, Chie Morioka, Yasuyuki Kihara, Shigeyuki Kawa, Masao Tanaka, Akira Andoh, Wataru Kimura, Isao Nishimori, Junji Furuse, Isao Yokota and Tooru Shimosegawa
Author ORCID Number
Hiroaki Yasuda http://orcid.org/0000-0002-8346-9853
Keisho Kataoka http://orcid.org/0000-0002-7227-3310
Yoshifumi Takeyama http://orcid.org/0000-0002-8034-6997
Kazunori Takeda http://orcid.org/0000-0002-0224-4848
Tetsuhide Ito http://orcid.org/0000-0001-5381-0136
Toshihiko Mayumi http://orcid.org/0000-0002-4462-9375
Shuji Isaji http://orcid.org/0000-0002-7683-6328
Tetsuya Mine http://orcid.org/0000-0001-6069-9747
Motoji Kitagawa http://orcid.org/0000-0003-4431-9390
Seiki Kiriyama http://orcid.org/0000-0001-8163-8783
Junichi Sakagami http://orcid.org/0000-0002-1219-4709
Atsushi Masamune http://orcid.org/0000-0001-7184-7282
Kazuo Inui http://orcid.org/0000-0002-0510-1412
Kenji Hirano http://orcid.org/0000-0002-7348-892X
Ryukichi Akashi http://orcid.org/0000-0002-9551-8720
Masamichi Yokoe http://orcid.org/0000-0002-6186-887X
Yoshio Sogame http://orcid.org/0000-0002-6919-5625
Kazuichi Okazaki http://orcid.org/0000-0003-3424-3142
Chie Morioka http://orcid.org/0000-0003-3088-9165
Yasuyuki Kihara http://orcid.org/0000-0001-5453-8699
Shigeyuki Kawa http://orcid.org/0000-0001-7870-9149
Masao Tanaka http://orcid.org/0000-0003-0995-0494
Akira Andoh http://orcid.org/0000-0001-8533-2669
Wataru Kimura http://orcid.org/0000-0001-8761-3667
Isao Nishimori http://orcid.org/0000-0003-4183-9243
Junji Furuse http://orcid.org/0000-0003-0663-6117
Isao Yokota http://orcid.org/0000-0001-6254-2225
Tooru Shimosegawa http://orcid.org/0000-0003-1255-5444
Funding Agency and Grant Number
Correspondence To Hiroaki Yasuda, MD, PhD, Doctor, Senior Lecturer, Department of Medicine, Division of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, 465 Kajii-cho Kawaramachi Hirokoji Kamigyo-ku, Kyoto 6028566, Japan. hiyasuda@koto.kpu-m.ac.jp
Keywords Acute pancreatitis; Trypsinogen activation peptide; Urinary trypsinogen-2 dipstick test
Core Tip A total of 94 patients with acute abdominal pain were enrolled from 17 medical institutions in Japan from April 2009 to December 2012. The trypsinogen-2 dipstick test was positive in 57 of 78 patients with acute pancreatitis (sensitivity, 73.1%) and in 6 of 16 patients with abdominal pain but without any evidence of acute pancreatitis (specificity, 62.5%). The levels of urinary trypsinogen-2 and trypsinogen activation peptide (TAP) were significantly higher in patients with extended extra-pancreatic inflammation as evaluated by CT Grade. Urinary trypsinogen-2 and TAP may be considered as additional markers to determine extra-pancreatic inflammation in acute pancreatitis.
Publish Date 2019-01-07 10:39
Citation Yasuda H, Kataoka L, Takeyama Y, Takeda K, Ito T, Mayumi T, Isaji S, Mine T, Kitagawa M, Kiriyama S, Sakagami J, Masamune A, Inui K, Hirano K, Akashi R, Yokoe M, Sogame Y, Okazaki K, Morioka C, Kihara Y, Kawa S, Tanaka M, Andoh A, Kimura W, Nishimori I, Furuse J, Yokota I, Shimosegawa T. Usefulness of urinary trypsinogen-2 and trypsinogen activation peptide in acute pancreatitis: A multicenter study in Japan. World J Gastroenterol 2019; 25(1): 107-117
Url https://www.wjgnet.com/1007-9327/full/v25/i1/107.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i1.107
Full Article (PDF) WJG-25-107.pdf
Full Article (Word) WJG-25-107.docx
Revised Manuscript 42853-Review.docx
Peer-review Report 42853-Peer-review(s).pdf
Answering Reviewers 42853-Answering reviewers.pdf
Scientific Editor Work List 42853-Scientific editor work list.pdf
Scientific Editor Work List 42853-Scientific misconduct check.pdf
Audio Core Tip 42853-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 42853-Conflict-of-interest statement.pdf
Copyright License Agreement 42853-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 42853-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 42853-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 42853-Language certificate.pdf