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3/7/2019 3:51:24 AM | Browse: 398 | Download: 362
Publication Name World Journal of Gastroenterology
Manuscript ID 43200
Country/Territory Germany
2018-10-30 01:55
Peer-Review Started
2018-11-01 01:01
To Make the First Decision
2018-12-05 05:59
Return for Revision
2018-12-17 07:06
2019-02-15 06:43
Second Decision
2019-02-15 09:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-02-16 02:56
Articles in Press
2019-02-16 02:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-03-06 09:14
Publish the Manuscript Online
2019-03-07 03:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Clinical Trials Study
Article Title Comprehensive lifestyle intervention vs soy protein-based meal regimen in non-alcoholic steatohepatitis
Manuscript Source Invited Manuscript
All Author List Peter Deibert, Adhara Lazaro, Denise Schaffner, Aloys Berg, Daniel Koenig, Wolfgang Kreisel, Manfred W Baumstark, Daniel Steinmann, Martin Buechert and Thomas Lange
Author(s) ORCID Number
Peter Deibert http://orcid.org/0000-0002-3291-884X
Adhara Lazaro http://orcid.org/0000-0001-9023-1387
Denise Schaffner http://orcid.org/0000-0001-6173-9288
Aloys Berg http://orcid.org/0000-0002-6794-9494
Daniel Koenig http://orcid.org/0000-0001-7002-1286
Wolfgang Kreisel http://orcid.org/0000-0001-6884-0135
Manfred W Baumstark http://orcid.org/0000-0002-5442-1586
Daniel Steinmann http://orcid.org/0000-0002-0374-6786
Martin Buechert http://orcid.org/0000-0001-5844-8711
Thomas Lange http://orcid.org/0000-0002-7467-8143
Funding Agency and Grant Number
Funding Agency Grant Number
Almased® Wellness Company, Bienenbuettel, Germany
Corresponding author Peter Deibert, MD, Professor, Institute for Exercise and Occupational Medicine, Faculty of Medicine, Medical Center-University of Freiburg, Hugstetter Str. 55, Freiburg 79106, Germany. peter.deibert@uniklinik-freiburg.de
Key Words Non-alcoholic steatohepatitis; Meal replacement therapy; Soy protein; Lifestyle change; Weight reduction; Obesity
Core Tip Non-alcoholic steatohepatitis (NASH) is a major cause of chronic liver disease. In obese patients weight reduction is recommended. We studied the effect of a soy protein-based meal replacement therapy and a therapeutic lifestyle intervention in a randomized controlled study of obese patients with NASH. Both groups significantly lost body fat and liver fat while muscle mass remained stable. Corresponding changes were found in blood lipids and adipokines. However, liver fat quality as mean chain length and saturation of lipids was modified differently by each intervention. The relevance of these findings has to be cleared by further studies.
Publish Date 2019-03-07 03:51
Citation Deibert P, Lazaro A, Schaffner D, Berg A, Koenig D, Kreisel W, Baumstark MW, Steinmann D, Buechert M, Lange T. Comprehensive lifestyle intervention vs soy protein-based meal regimen in non-alcoholic steatohepatitis. World J Gastroenterol 2019; 25(9): 1116-1131
Url https://www.wjgnet.com/1007-9327/full/v25/i9/1116.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i9.1116
Full Article (PDF) WJG-25-1116.pdf
Full Article (Word) WJG-25-1116.docx
Manuscript File 43200-Review.docx
Answering Reviewers 43200-Answering reviewers.pdf
Audio Core Tip 43200-Audio core tip.mp3
Biostatistics Review Certificate 43200-Biostatistics statement.pdf
Clinical Trial Registration Statement 43200-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 43200-Conflict-of-interest statement.pdf
Copyright License Agreement 43200-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 43200-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 43200-Institutional review board statement.pdf
Peer-review Report 43200-Peer-review(s).pdf
Scientific Misconduct Check 43200-Scientific misconduct check.pdf
Scientific Editor Work List 43200-Scientific editor work list.pdf