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Publication Name World Journal of Experimental Medicine
Manuscript ID 4365
Country/Territory Greece
Received
2013-06-28 11:09
Peer-Review Started
2013-06-28 17:09
To Make the First Decision
2013-08-08 11:10
Return for Revision
2013-08-15 09:34
Revised
2013-09-06 16:39
Second Decision
2013-11-01 16:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-11-03 11:07
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-11-18 11:51
Publish the Manuscript Online
2013-11-20 17:44
ISSN 2220-315x (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry & Molecular Biology
Manuscript Type Review
Article Title Mechanotransduction in bone: Intervening in health and disease
Manuscript Source Invited Manuscript
All Author List Anastasia Spyropoulou and Efthimia K Basdra
Funding Agency and Grant Number
Corresponding Author Efthimia K Basdra, PhD, Associate Professor, Department of Biological Chemistry, Cellular and Molecular Biomechanics Unit, University of Athens Medical School, 75, M. Asias Street, GR-11527 Athens, Greece. tegk.84@gmail.com
Key Words Mechanotransduction; Bone remodeling; Bone disease; Bone health
Core Tip Mechanotransduction has been shown to be of major significance in modulating bone remodeling under physiological and pathological conditions. Therefore the study of the underlying mechanisms is of major importance and necessary step towards the better understanding of bone biology as well as the development of therapeutic strategies against conditions characterised by deregulated mechanotransduction. This review will consider the molecular mechanisms behind mechanotransduction as well as the scientific models currently used for its better understanding. It will also focus on mechanostimulatory techniques that could be used against a variety of deregulated mechanotransduction-related diseases.
Publish Date 2013-11-20 17:44
Citation Spyropoulou A, Basdra EK. Mechanotransduction in bone: Intervening in health and disease. World J Exp Med 2013; 3(4): 74-86
URL http://www.wjgnet.com/2220-315X/full/v3/i4/74.htm
DOI http://dx.doi.org/10.5493/wjem.v3.i4.74
Full Article (PDF) WJEM-3-74.pdf
Manuscript File 4365-Review.docx
Answering Reviewers 4365-Answering reviewers.pdf
Copyright License Agreement 4365-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 4365-Language certificate.PDF
Peer-review Report 4365-Peer review(s).pdf
Scientific Editor Work List 4365-Scientific editor work list.doc