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10/16/2019 12:17:24 PM | Browse: 584 | Download: 575
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 46449
Country United States
Received
2019-02-27 03:29
Peer-Review Started
2019-02-27 12:12
To Make the First Decision
2019-04-12 00:45
Return for Revision
2019-04-24 07:16
Revised
2019-05-01 13:00
Second Decision
2019-09-12 09:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-09-12 17:07
Articles in Press
2019-09-12 17:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-10-12 11:32
Publish the Manuscript Online
2019-10-16 12:17
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Retrospective review of total neoadjuvant therapy
Manuscript Source Unsolicited Manuscript
All Author List Laila Babar, Veli Bakalov, Stephen Abel, Obaid Ashraf, Gene Grant Finley, Moses S Raj, Kristina Lundeen, Dulabh K Monga, Alexander V Kirichenko and Rodney E Wegner
ORCID
Author(s) ORCID Number
Laila Babar http://orcid.org/0000-0003-1520-8798
Veli Bakalov http://orcid.org/0000-0002-2472-5546
Stephen Abel http://orcid.org/0000-0003-4956-8900
Obaid Ashraf http://orcid.org/0000-0002-2138-4475
Gene Grant Finley http://orcid.org/0000-0003-1987-1781
Moses S Raj http://orcid.org/0000-0002-4779-3306
Kristina Lundeen http://orcid.org/0000-0002-3254-1886
Dulabh K Monga http://orcid.org/0000-0002-2242-4643
Alexander V Kirichenko http://orcid.org/0000-0002-4432-1039
Rodney E Wegner http://orcid.org/0000-0003-2416-3499
Funding Agency and Grant Number
Corresponding Author Laila Babar, MD, Doctor, Department of Internal Medicine, Allegheny General Hospital, 320 E North Ave, Pittsburgh, PA 15212, United States. laila.babar@ahn.org
Key Words Total neoadjuvant therapy; Neoadjuvant chemoradiation; Multi-agent chemotherapy; Locally advanced rectal cancer; National cancer database; Colorectal cancer
Core Tip Total neoadjuvant treatment (TNT) has been gaining favor as the treatment of choice for rectal carcinoma. It has been linked to better sphincter preservation and overall improved quality of life. Our study aim was to compare TNT with traditional chemotherapy and radiation over the last 10 years and evaluate for differences in outcome. Our study confirms a rising trend in the of use of TNT especially in patients diagnosed with locally advanced rectal cancer. Patients treated with TNT had higher burden of disease and despite this, they had similar survival outcomes as those treated with traditional chemotherapy and radiation.
Publish Date 2019-10-16 12:17
Citation Babar L, Bakalov V, Abel S, Ashraf O, Finley GG, Raj MS, Lundeen K, Monga DK, Kirichenko AV, Wegner RE. Retrospective review of total neoadjuvant therapy. World J Gastrointest Oncol 2019; 11(10): 857-865
URL https://www.wjgnet.com/1948-5204/full/v11/i10/857.htm
DOI https://dx.doi.org/10.4251/wjgo.v11.i10.857
Full Article (PDF) WJGO-11-857.pdf
Full Article (Word) WJGO-11-857.docx
Manuscript File 46449-Review.docx
Answering Reviewers 46449-Answering reviewers.pdf
Audio Core Tip 46449-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 46449-Conflict-of-interest statement.pdf
Copyright License Agreement 46449-Copyright license agreement.PDF
Institutional Review Board Approval Form or Document 46449-Institutional review board statement.pdf
Peer-review Report 46449-Peer-review(s).pdf
Scientific Misconduct Check 46449-Scientific misconduct check.pdf
Scientific Editor Work List 46449-Scientific editor work list.pdf