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Articles Published Processes
11/28/2019 8:04:08 AM | Browse: 604 | Download: 900
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Received |
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2019-02-27 01:29 |
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Peer-Review Started |
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2019-02-27 12:48 |
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To Make the First Decision |
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2019-08-06 02:56 |
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Return for Revision |
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2019-08-20 02:31 |
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Revised |
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2019-10-14 04:24 |
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Second Decision |
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2019-10-24 01:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-11-05 04:44 |
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Articles in Press |
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2019-11-05 04:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-11-15 01:55 |
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Typeset the Manuscript |
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2019-11-27 02:20 |
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Publish the Manuscript Online |
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2019-11-28 08:04 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Anti-osteoarthritis effect of a combinational treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kyungha Shin, Yeseul Cha, Young-Hwan Ban, Da Woom Seo, Ehn-Kyoung Choi, Dongsun Park, Sung Keun Kang, Jeong Chan Ra and Yun-Bae Kim |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Research Foundation of Korea (NRF) |
2017R1A2A2A05069417 |
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| Corresponding Author |
Yun-Bae Kim, DVM, PhD, Professor, College of Veterinary Medicine, Chungbuk National University, 1 Chungdaero (Gaesin-dong), Cheongju 28644, Chungbuk, South Korea. solar93@cbu.ac.kr |
| Key Words |
Osteoarthrits; Anterior cruciate ligament transection; Human adipose tissue-derived mesenchymal stem cell; Thrombospondin 2; Notch signaling; Cartilage regeneration |
| Core Tip |
We demonstrated the role of thrombospondin 2 (TSP2) in the chondrogenic differentiation of human adipose-derived MSCs (hADMSCs) in vitro and in OA therapy with the cells in vivo. TSP2 induced chondrogenic differentiation via JAGGED1/NOTCH signaling, and potentiated the cartilage-restoring efficacy of hADMSCs. |
| Publish Date |
2019-11-28 08:04 |
| Citation |
Shin K, Cha Y, Ban YH, Seo DW, Choi EK, Park D, Kang SK, Ra JC, Kim YB. Anti-osteoarthritis effect of a combinational treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits. World J Stem Cells 2019; 11(12): 1115-1129 |
| URL |
https://www.wjgnet.com/1948-0210/full/v11/i12/1115.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v11.i12.1115 |
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