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11/28/2019 8:04:08 AM | Browse: 14 | Download: 35
Publication Name World Journal of Stem Cells
Manuscript ID 46573
Country of Manuscript Source South Korea
Received
2019-02-27 01:29
Peer-Review Started
2019-02-27 12:48
To Make the First Decision
2019-08-06 02:56
Return for Revision
2019-08-20 02:31
Revised
2019-10-14 04:24
Second Decision
2019-10-24 01:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-11-05 04:44
Articles in Press
2019-11-05 04:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-11-15 01:55
Typeset the Manuscript
2019-11-27 02:20
Publish the Manuscript Online
2019-11-28 08:04
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Cell Biology
Manuscript Type Basic Study
Article Title Anti-osteoarthritis effect of a combinational treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits
Manuscript Source Invited Manuscript
All Author List Kyungha Shin, Yeseul Cha, Young-Hwan Ban, Da Woom Seo, Ehn-Kyoung Choi, Dongsun Park, Sung Keun Kang, Jeong Chan Ra and Yun-Bae Kim
ORCID
Author(s) ORCID Number
Kyungha Shin http://orcid.org/0000-0001-7843-4798
Yeseul Cha http://orcid.org/0000-0002-5263-9290
Young-Hwan Ban http://orcid.org/0000-0003-2219-3299
Da Woom Seo http://orcid.org/0000-0002-1541-8800
Ehn-Kyoung Choi http://orcid.org/0000-0002-6112-6622
Dongsun Park http://orcid.org/0000-0001-6042-5949
Sung Keun Kang http://orcid.org/0000-0003-4387-6363
Jeong Chan Ra http://orcid.org/0000-0002-6982-5348
Yun-Bae Kim http://orcid.org/0000-0003-1340-041X
Funding Agency and Grant Number
Funding Agency Grant Number
National Research Foundation of Korea (NRF) 2017R1A2A2A05069417
Corresponding author Yun-Bae Kim, DVM, PhD, Professor, College of Veterinary Medicine, Chungbuk National University, 1 Chungdaero (Gaesin-dong), Cheongju 28644, Chungbuk, South Korea. solar93@cbu.ac.kr
Keywords Osteoarthrits; Anterior cruciate ligament transection; Human adipose tissue-derived mesenchymal stem cell; Thrombospondin 2; Notch signaling; Cartilage regeneration
Core Tip We demonstrated the role of thrombospondin 2 (TSP2) in the chondrogenic differentiation of human adipose-derived MSCs (hADMSCs) in vitro and in OA therapy with the cells in vivo. TSP2 induced chondrogenic differentiation via JAGGED1/NOTCH signaling, and potentiated the cartilage-restoring efficacy of hADMSCs.
Publish Date 2019-11-28 08:04
Citation Shin K, Cha Y, Ban YH, Seo DW, Choi EK, Park D, Kang SK, Ra JC, Kim YB. Anti-osteoarthritis effect of a combinational treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits. World J Stem Cells 2019; 11(12): 1115-1129
Url https://www.wjgnet.com/1948-0210/full/v11/i12/1115.htm
DOI https://dx.doi.org/10.4252/wjsc.v11.i12.1115
Full Article (PDF) WJSC-11-1115.pdf
Full Article (Word) WJSC-11-1115.docx
Manuscript File FP7073_ce36_CE1MS_edit2(191112_191114).doc
Answering Reviewers 46573-Answering reviewers.pdf
Audio Core Tip 46573-Audio core tip.m4a
Biostatistics Review Certificate 46573-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 46573-Conflict-of-interest statement.pdf
Copyright License Agreement 46573-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 46573-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 46573-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 46573-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 46573-Language certificate.pdf
Supplementary Material 46573-Supplementary material.pdf
Peer-review Report 46573-Peer-review(s).pdf
Scientific Editor Work List 46573-Scientific editor work list.pdf