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6/6/2019 8:31:40 AM | Browse: 72 | Download: 49
Publication Name World Journal of Gastroenterology
Manuscript ID 47009
Country of Manuscript Source China
2019-03-12 08:16
Peer-Review Started
2019-03-13 00:49
To Make the First Decision
2019-04-11 08:18
Return for Revision
2019-04-12 01:40
2019-04-21 05:22
Second Decision
2019-04-30 09:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-03 12:01
Articles in Press
2019-05-03 12:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-05-08 02:29
Typeset the Manuscript
2019-06-03 05:54
Publish the Manuscript Online
2019-06-06 08:31
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Meta-Analysis
Article Title Association of proton pump inhibitors with the risk of hepatic encephalopathy in advanced liver disease: A meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Xin-Xing Tantai, Long-Bao Yang, Zhong-Cao Wei, Cai-Lan Xiao, Li-Rong Chen, Jin-Hai Wang and Na Liu
Author(s) ORCID Number
Xin-Xing Tantai http://orcid.org/0000-0002-4105-6890
Long-Bao Yang http://orcid.org/0000-0001-7731-0910
Zhong-Cao Wei http://orcid.org/0000-0001-8931-680X
Cai-Lan Xiao http://orcid.org/0000-0001-8476-5008
Li-Rong Chen http://orcid.org/0000-0001-8901-2830
Jin-Hai Wang http://orcid.org/0000-0003-1365-4727
Na Liu http://orcid.org/0000-0003-3246-9674
Funding Agency and Grant Number
Correspondence To Na Liu, PhD, Doctor, Division of Gastroenterology, The Second Affiliated Hospital, Xi’an Jiaotong University, No. 157, Xi Wu Road, Xi’an 710004, Shaanxi Province, China. liunafmmu@163.com
Keywords Proton pump inhibitors; Cirrhosis; Hepatic encephalopathy; Systematic review; Meta-analysis
Core Tip Proton pump inhibitors (PPIs) are very commonly used in patients with advanced liver disease. Remarkably, previous studies have shown that approximately 50% of indications for PPIs treatment were unclear or inadequate in this special group of patients. All this may be because PPIs are generally considered safe. However, this meta-analysis shows that using PPIs is associated with an increased risk of hepatic encephalopathy (HE) in patients with advanced liver disease. This reminds clinicians that inappropriate use of PPIs may be not beneficial but put patients at an elevated risk of HE. These findings still need to be confirmed by more high-quality prospective studies because of the limitations of this meta-analysis.
Publish Date 2019-06-06 08:31
Citation Tantai XX, Yang LB, Wei ZC, Xiao CL, Chen LR, Wang JH, Liu N. Association of proton pump inhibitors with the risk of hepatic encephalopathy in advanced liver disease: A meta-analysis. World J Gastroenterol 2019; 25(21): 2683-2698
Url https://www.wjgnet.com/1007-9327/full/v25/i21/2683.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i21.2683
Full Article (PDF) WJG-25-2683.pdf
Full Article (Word) WJG-25-2683.docx
Manuscript File 47009-Review_Edited.docx
Answering Reviewers 47009-Answering reviewers.pdf
Audio Core Tip 47009-Audio core tip.mp3
Biostatistics Review Certificate 47009-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 47009-Conflict-of-interest statement.pdf
Copyright License Agreement 47009-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 47009-Language certificate.pdf
Peer-review Report 47009-Peer-review(s).pdf
Scientific Misconduct Check 47009-Scientific misconduct check.pdf
Scientific Editor Work List 47009-Scientific editor work list.pdf