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9/7/2019 4:43:36 AM | Browse: 77 | Download: 182
Publication Name World Journal of Gastroenterology
Manuscript ID 48232
Country of Manuscript Source Italy
2019-04-11 00:37
Peer-Review Started
2019-04-11 05:34
To Make the First Decision
2019-05-17 00:26
Return for Revision
2019-05-24 06:44
2019-05-31 10:10
Second Decision
2019-06-05 10:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-06-08 14:56
Articles in Press
2019-06-08 14:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-09-04 01:08
Publish the Manuscript Online
2019-09-07 04:43
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Ex vivo effect of vascular wall stromal cells secretome on enteric ganglia
Manuscript Source Unsolicited Manuscript
All Author List Giovanni Dothel, Chiara Bernardini, Augusta Zannoni, Maria Rosaria Spirito, Roberta Salaroli, Maria Laura Bacci, Monica Forni and Fabrizio De Ponti
Author(s) ORCID Number
Giovanni Dothel http://orcid.org/0000-0002-8588-9018
Chiara Bernardini http://orcid.org/0000-0003-3384-0244
Augusta Zannoni http://orcid.org/0000-0002-2972-4921
Maria Rosaria Spirito http://orcid.org/0000-0003-1963-5340
Roberta Salaroli http://orcid.org/0000-0002-8819-2857
Maria Laura Bacci http://orcid.org/0000-0001-6702-5868
Monica Forni http://orcid.org/0000-0003-1310-6202
Fabrizio De Ponti http://orcid.org/0000-0002-0367-9595
Funding Agency and Grant Number
Funding Agency Grant Number
Fondazione del Monte di Bologna e Ravenna FdM/3208
Corresponding author Monica Forni, PhD, Associate Professor, Professor, Department of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, Bologna 40064, Italy. monica.forni@unibo.it
Keywords Enteric nervous system; Mesenchymal stromal cells; Inflammatory bowel disease; Ganglia; Translational models;
Core Tip Secretome of porcine vascular wall mesenchymal stromal cells (pVW-MSCs) induced an increase of glial cell number in swine and guinea pig-derived enteric ganglia. Co-treatment of enteric ganglia with lipopolysaccharide and conditioned medium promoted glial cell differentiation only in pigs. These data indicate an immune activation promoted by pVW-MSCs which could be more specific in higher mammals, suggesting a careful consideration of the animal models used in research studies on cell-based therapies.
Publish Date 2019-09-07 04:43
Citation Dothel G, Bernardini C, Zannoni A, Spirito MR, Salaroli R, Bacci ML, Forni M, De Ponti F. Ex vivo effect of vascular wall stromal cells secretome on enteric ganglia. World J Gastroenterol 2019; 25(33): 4892-4903
Url https://www.wjgnet.com/1007-9327/full/v25/i33/4892.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i33.4892
Full Article (PDF) WJG-25-4892.pdf
Full Article (Word) WJG-25-4892.docx
Manuscript File 48232-Review.docx
Answering Reviewers 48232-Answering reviewers.pdf
Audio Core Tip 48232-Audio core tip.mp3
Biostatistics Review Certificate 48232-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 48232-Conflict-of-interest statement.pdf
Copyright License Agreement 48232-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 48232-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 48232-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 48232-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 48232-Language certificate.pdf
Peer-review Report 48232-Peer-review(s).pdf
Scientific Misconduct Check 48232-Scientific misconduct check.pdf
Scientific Editor Work List 48232-Scientific editor work list.pdf