Publication Name	World Journal of Gastroenterology
Manuscript ID	4908
Country	Japan

Received	2013-08-01 11:57
Peer-Review Started	2013-08-02 01:50
First Decision by Editorial Office Director
Return for Revision	2013-08-29 14:54
Revised	2013-09-09 07:48
Publication Fee Transferred
Second Decision by Editor	2013-11-04 18:05
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-11-05 10:34
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-10 14:54
Publish the Manuscript Online	2014-01-19 14:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
Manuscript Source	Invited Manuscript
All Author List	Yoshio Sumida, Atsushi Nakajima and Yoshito Itoh
Funding Agency and Grant Number	Funding Agency Grant Number MSD Co., Ltd. to Sumida Y MSD Co., Ltd. to Ioh Y Dainippon Sumitomo Pharma Co., Ltd. to Ioh Y
Corresponding Author	Yoshio Sumida, MD, PhD, Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan. sumida@koto.kpu-m.ac.jp
Key Words	Nonalcoholic fatty liver disease; Liver biopsy; Steatosis; Fibrosis; Nonalcoholic steatohepatitis
Core Tip	Liver biopsies remain a gold standard, although the procedure has several limitations for the diagnosis of nonalcoholic steatohepatitis (NASH). The NAFIC score, calculated from the levels of ferritin, fasting insulin and type Ⅳ collagen 7S, is useful for diagnosing NASH, while the nonalcoholic fatty liver disease fibrosis score and the FIB-4 index are useful for excluding NASH in cases of advanced fibrosis.
Publish Date	2014-01-19 14:17
Citation	Sumida Y, Nakajima A, Itoh Y. Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Gastroenterol 2014; 20(2): 475-485
URL	http://www.wjgnet.com/1007-9327/full/v20/i2/475.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i2.475

Full Article (PDF)	WJG-20-475.pdf
Full Article (Word)	WJG-20-475.doc
Manuscript File	4908-Review.docx
Answering Reviewers	4908-Answering reviewers.pdf
Copyright License Agreement	4908-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4908-Language certificate.pdf
Peer-review Report	4908-Peer reviewer(s).pdf
Scientific Editor Work List	4908-Scientific editor work list.doc