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Articles Published Processes
9/4/2014 3:52:00 PM | Browse: 1014 | Download: 986
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Received |
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2013-08-01 11:57 |
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Peer-Review Started |
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2013-08-02 01:50 |
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To Make the First Decision |
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2013-08-21 18:51 |
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Return for Revision |
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2013-08-29 14:54 |
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Revised |
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2013-09-09 07:48 |
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Second Decision |
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2013-11-04 18:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2013-11-05 10:34 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-01-10 14:54 |
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Publish the Manuscript Online |
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2014-01-19 14:17 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
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Manuscript Source |
Invited Manuscript |
All Author List |
Yoshio Sumida, Atsushi Nakajima and Yoshito Itoh |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
MSD Co., Ltd. |
to Sumida Y |
MSD Co., Ltd. |
to Ioh Y |
Dainippon Sumitomo Pharma Co., Ltd. |
to Ioh Y |
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Corresponding Author |
Yoshio Sumida, MD, PhD, Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan. sumida@koto.kpu-m.ac.jp
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Key Words |
Nonalcoholic fatty liver disease; Liver biopsy; Steatosis; Fibrosis; Nonalcoholic steatohepatitis |
Core Tip |
Liver biopsies remain a gold standard, although the procedure has several limitations for the diagnosis of nonalcoholic steatohepatitis (NASH). The NAFIC score, calculated from the levels of ferritin, fasting insulin and type Ⅳ collagen 7S, is useful for diagnosing NASH, while the nonalcoholic fatty liver disease fibrosis score and the FIB-4 index are useful for excluding NASH in cases of advanced fibrosis.
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Publish Date |
2014-01-19 14:17 |
Citation |
Sumida Y, Nakajima A, Itoh Y. Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Gastroenterol 2014; 20(2): 475-485 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i2/475.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i2.475 |
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