| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Salvatore Magrì, Danilo Paduano, Fabio Chicco, Arianna Cingolani, Cristiana Farris, Giovanna Delogu, Francesca Tumbarello, Alessandro Melis, Mariantonia Lai, Laura Casula, Massimo C Fantini and Paolo Usai |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Salvatore Magrì, MD, Doctor, Occupational Physician, Staff Physician, Department of Medical Sciences and Public Health, University of Cagliari, Presidio Policlinico of Monserrato, Cagliari, SS 554 km 4,500, Monserrato 09042, Italy. salvo10ms@libero.it |
| Key Words |
Nonalcoholic fatty liver disease; Liver fibrosis; Inflammatory bowel disease; Risk factors; Dietary habits; |
| Core Tip |
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, frequently reported in patients with inflammatory bowel disease (IBD). The underlining causes and predisposing factors to NAFLD among IBD patients remain poorly investigated. We performed an observational study enrolling consecutive IBD patients to evaluate the prevalence of steatosis and liver fibrosis and their association with IBD-related risk factors. Our study confirms the epidemiological burden of NAFLD in IBD and demonstrates the absence of intestinal disease-specific risk factors associated to NAFLD, while confirming as risk factors those already identified in the general population. IBD care should not be limited to intestinal disease but should also include metabolic interventions by promoting healthy lifestyle and a correct dietary regimen in order to reduce the occurrence of chronic liver disease. |
| Publish Date |
2019-09-30 02:14 |
| Citation |
Magrì S, Paduano D, Chicco F, Cingolani A, Farris C, Delogu G, Tumbarello F, Lai M, Melis A, Casula L, Fantini MC, Usai P. Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history. World J Gastroenterol 2019; 25(37): 5676-5686 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i37/5676.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i37.5676 |
