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11/7/2019 1:35:59 AM | Browse: 668 | Download: 1282
Publication Name World Journal of Gastroenterology
Manuscript ID 51101
Country China
Received
2019-08-27 09:45
Peer-Review Started
2019-08-27 09:47
To Make the First Decision
2019-09-19 06:33
Return for Revision
2019-09-20 03:31
Revised
2019-10-11 15:19
Second Decision
2019-10-16 12:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-10-21 18:12
Articles in Press
2019-10-21 18:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-10-31 01:15
Typeset the Manuscript
2019-11-05 00:01
Publish the Manuscript Online
2019-11-07 01:35
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry & Molecular Biology
Manuscript Type Basic Study
Article Title MiR-32-5p aggravates intestinal epithelial cell injury of pediatric enteritis induced by Helicobacter pylori
Manuscript Source Unsolicited Manuscript
All Author List Jing Feng, Jian Guo, Jun-Ping Wang and Bao-Feng Chai
ORCID
Author(s) ORCID Number
Jing Feng http://orcid.org/0000-0001-9440-1136
Jian Guo http://orcid.org/0000-0002-4409-0066
Jun-Ping Wang http://orcid.org/0000-0002-1586-2776
Bao-Feng Chai http://orcid.org/0000-0001-7625-8217
Funding Agency and Grant Number
Corresponding Author Bao-Feng Chai, MD, PhD, Professor, Department of Gastroenterology, Shanxi Provincial People's Hospital, The Affiliated People's Hospital of Shanxi Medical University, NO. 29, Shuangtasi Street, Taiyuan 030012, China. 13644359409@163.com
Key Words MiR-32-5p; SMAD family member 6; Transforming growth factor-β-activated kinase 1; Apoptosis; Enteritis; Helicobacter pylori
Core Tip Our study demonstrated the harmful role of aberrant miR-35-5p in H. pylori-infected intestinal epithelial cells. Further investigation showed SMAD6 was the downstream of miR-32-5p and exerted the opposite role in this process. What’s more, miR-32-5p/SMAD6 contributed to TGF-β1-TAK1-p38 cascade in intestinal epithelial cells under H. pylori infection. These findings revealed a novel insight into the pathogenesis of pediatric enteritis caused by H. pylori.
Publish Date 2019-11-07 01:35
Citation Feng J, Guo J, Wang JP, Chai BF. miR-32-5p aggravates intestinal epithelial cell injury of pediatric enteritis induced by Helicobacter pylori. World J Gastroenterol 2019; 25(41): 6222-6237
URL https://www.wjgnet.com/1007-9327/full/v25/i41/6222.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i41.6222
Full Article (PDF) WJG-25-6222.pdf
Full Article (Word) WJG-25-6222.docx
Manuscript File 51101-Review_Edited.docx
Answering Reviewers 51101-Answering reviewers.pdf
Audio Core Tip 51101-Audio core tip.mp3
Biostatistics Review Certificate 51101-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 51101-Conflict-of-interest statement.pdf
Copyright License Agreement 51101-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 51101-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 51101-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 51101-Language certificate.pdf
Peer-review Report 51101-Peer-review(s).pdf
Scientific Misconduct Check 51101-Scientific misconduct check.pdf
Scientific Editor Work List 51101-Scientific editor work list.pdf