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6/14/2020 1:45:26 PM | Browse: 102 | Download: 104
Publication Name World Journal of Gastroenterology
Manuscript ID 53429
Country/Territory Romania
Received
2019-12-28 07:52
Peer-Review Started
2019-12-19 10:26
To Make the First Decision
Return for Revision
2020-01-19 00:43
Revised
2020-05-14 08:10
Second Decision
2020-05-27 05:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-28 03:05
Articles in Press
2020-05-28 03:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-06-11 01:33
Publish the Manuscript Online
2020-06-14 13:45
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title High plasma levels of COL10A1 are associated with advanced tumor stage in gastric cancer patients
Manuscript Source Invited Manuscript
All Author List Laura Necula, Lilia Matei, Denisa L Dragu, Ioana Pitica, Ana I Neagu, Coralia Bleotu, Simona Dima, Irinel Popescu, Carmen C Diaconu and Mihaela Chivu-Economescu
ORCID
Author(s) ORCID Number
Laura Necula http://orcid.org/0000-0001-6531-7939
Lilia Matei http://orcid.org/0000-0003-4479-655X
Denisa L Dragu http://orcid.org/0000-0002-5868-2636
Ioana Pitica http://orcid.org/0000-0001-7440-9798
Ana I Neagu http://orcid.org/0000-0001-6126-8973
Coralia Bleotu http://orcid.org/0000-0002-9031-338X
Simona Dima http://orcid.org/0000-0001-5275-8938
Irinel Popescu http://orcid.org/0000-0002-2897-1170
Carmen C Diaconu http://orcid.org/0000-0002-2259-1425
Mihaela Chivu-Economescu http://orcid.org/0000-0001-7512-4700
Funding Agency and Grant Number
Funding Agency Grant Number
Romanian National Authority for Scientific Research and Innovation, CNCS - UEFISCDI PN-III-P4-ID-PCCF2016-0158
Corresponding author Mihaela Chivu-Economescu, PhD, Research Assistant Professor, Research Scientist, Senior Researcher, Department of Cellular and Molecular Pathology, Stefan S. Nicolau Institute of Virology, 285 Mihai Bravu Ave, Bucharest 030304, Romania. mihaela.economescu@virology.ro
Key Words Gastric cancer; COL10A1; Circulating biomarkers; Early diagnosis; Poor prognosis; Tumor stage
Core Tip Gastric cancer remains an aggressive malignancy with a high rate of mortality, characterized by limited effective treatment options and the lack of consistent biomarkers for the diagnosis and prognosis of the patients. The aim of this study was to evaluate the potential of COL10A1 as a circulating biomarker for the diagnosis and prognosis of gastric adenocarcinoma patients. Our results suggest that COL10A1 could be considered a good biomarker for prognosis and also for early detection, as its elevated expression occurred early and remained elevated during cancer progression.
Publish Date 2020-06-14 13:45
Citation Necula L, Matei L, Dragu D, Pitica I, Neagu AI, Bleotu C, Dima S, Popescu I, Diaconu CC, Chivu-Economescu M. High plasma levels of COL10A1 are associated with advanced tumor stage in gastric cancer patients. World J Gastroenterol 2020; 26(22): 3024-3033
Url https://www.wjgnet.com/1007-9327/full/v26/i22/3024.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i22.3024
Full Article (PDF) WJG-26-3024.pdf
Full Article (Word) WJG-26-3024.docx
Manuscript File 53429-Review.docx
Answering Reviewers 53429-Answering reviewers.pdf
Audio Core Tip 53429-Audio core tip.mp3
Biostatistics Review Certificate 53429-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 53429-Conflict-of-interest statement.PDF
Copyright License Agreement 53429-Copyright license agreement.PDF
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 53429-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 53429-Institutional review board statement.PDF
Non-Native Speakers of English Editing Certificate 53429-Language certificate.pdf
Peer-review Report 53429-Peer-review(s).pdf
Scientific Misconduct Check 53429-Scientific misconduct check.pdf
Scientific Editor Work List 53429-Scientific editor work list.pdf